Variations in working memory capacity predict individual differences in general learning abilities among genetically diverse mice
Variations in working memory capacity predict individual differences in general learning abilities among genetically diverse mice
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DOI：
10.1016/j.nlm.2005.07.006
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发表时间：
2005-11-01
影响因子：
2.7
通讯作者：
Matzel, LD
中科院分区：
文献类型：
--
作者：
Kolata, S;Light, K;Matzel, LD
一个人在各种不同的认知测试中的表现，高达50%可以用一个因素（即“一般智力”）来解释。尽管它无处不在，但调节这一因素的过程或机制是一个相当有争议的问题。尽管人们假设工作记忆可能会影响各个领域的认知表现，但由于很难将工作记忆与其重叠的操作（如语言能力）分离开来，测试一直没有定论。我们用基因多样化的老鼠来解决这个问题，这些老鼠表现出类似于一般智力的特征。CD-1小鼠的一般认知能力与个体的工作记忆容量有关，但与长期记忆的变化无关。这些结果提供了独立于语言能力的证据，表明工作记忆的变化与一般认知能力有关，并且进一步表明调节认知能力的机制和/或过程在物种之间是守恒的。(c) 2005爱思唯尔公司版权所有。
Up to 50% of an individuals' performance across a wide variety of distinct cognitive tests can be accounted for by a single factor (i.e., "general intelligence"). Despite its ubiquity, the processes or mechanisms regulating this factor are a matter of considerable debate. Although it has been hypothesized that working memory may impact cognitive performance across various domains, tests have been inconclusive due to the difficultly in isolating working memory from its overlapping operations, such as verbal ability. We address this problem using genetically diverse mice, which exhibit a trait analogous to general intelligence. The general cognitive abilities of CD-1 mice were found to covary with individuals' working memory capacity, but not with variations in long-term retention. These results provide evidence that independent of verbal abilities, variations in working memory are associated with general cognitive abilities, and further, suggest a conservation across species of mechanisms and/or processes that regulate cognitive abilities. (c) 2005 Elsevier Inc. All rights reserved.