Thermally mediated droplet formation in microchannels
Thermally mediated droplet formation in microchannels
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DOI：
10.1063/1.2773948
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发表时间：
2007-08
影响因子：
4
通讯作者：
N. Nguyen;T. H. Ting;Y. Yap;T. Wong;J. Chai;W. Ong;Jun Zhou;S. Tan;L. Yobas
中科院分区：
文献类型：
--
作者：
N. Nguyen;T. H. Ting;Y. Yap;T. Wong;J. Chai;W. Ong;Jun Zhou;S. Tan;L. Yobas
微液滴的精确点胶是基于液滴的微流控系统的一个重要环节。两种不互溶流体之间的剪切力形成液滴取决于它们的流速、粘度和界面张力。在这封信中，作者报告了使用集成微加热器和温度传感器来控制液滴形成过程。该技术利用粘度和界面张力对温度的依赖性。使用范围为25至70 ° C的相对低的加热温度，可以将液滴直径调节到其原始值的两倍以上。相对低的温度范围确保了该概念适用于包含生物样品的液滴。
Precise dispensing of microdroplets is an important process for droplet-based microfluidics. The dropletformation by shear force between two immiscible fluids depends on their flow rates, the viscosities, and the interfacial tension. In this letter, the authors report the use of integrated microheater and temperature sensor for controlling the dropletformation process. The technique exploits the dependency on temperature of viscosities and interfacial tension. Using a relatively low heating temperature ranging from 25 to 70 ° C , the droplet diameter can be adjusted to over two times of its original value. The relatively low temperature range makes sure that this concept is applicable for droplets containing biological samples.