Microwave imaging via space-time beamforming for early detection of breast cancer
Microwave imaging via space-time beamforming for early detection of breast cancer
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DOI：
10.1109/tap.2003.815446
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发表时间：
2003-08-01
影响因子：
5.7
通讯作者：
Van Veen, BD
中科院分区：
文献类型：
--
作者：
Bond, EJ;Li, X;Van Veen, BD
提出了一种基于微波空时成像（MIST）波束形成的早期乳腺癌检测方法。天线阵列位于乳房表面附近，并且从每个天线顺序地发射超宽带（UWB）信号。所接收的反向散射信号通过空时波束形成器，该空时波束形成器被设计成将反向散射信号能量成像为位置的函数。波束形成器在空间上聚焦后向散射信号，以区分杂波和噪声，同时补偿频率相关的传播效应。由于正常组织和恶性组织之间的显著介电性质对比，图像中的大反向散射能级的局部区域对应于恶性肿瘤。一个数据自适应算法，用于消除由于从皮肤-乳房界面的反向散射在接收到的信号中的伪影。这些算法的有效性证明了使用各种数值乳房幻影解剖现实的MRI派生的FDTD模型的乳房。非常小（2 mm）的恶性肿瘤嵌入在复杂的纤维腺体结构的乳房很容易检测到以上的背景杂波。的MIST的方法被证明是提供显着的改善性能比以前的UWB微波乳腺癌检测技术的基础上更简单的聚焦计划。
A method of microwave imaging via space-time (MIST) beamforming is proposed for detecting early-stage breast cancer. An array of antennas is located near the surface of the breast and an ultrawideband (UWB) signal is transmitted sequentially from each antenna. The received backscattered signals are passed through a space-time beamformer that is designed to image backscattered signal energy as a function of location. The beamformer spatially focuses the backscattered signals to discriminate against clutter and noise while compensating for frequency-dependent propagation effects. As a consequence of the significant dielectric-properties contrast between normal and malignant tissue, localized regions of large backscatter energy levels in the image correspond to malignant tumors. A data-adaptive algorithm for removing artifacts in the received signals due to backscatter from the skin-breast interface is also presented. The effectiveness of these algorithms is demonstrated using a variety of numerical breast phantoms based on anatomically realistic MRI-derived FDTD models of the breast. Very small (2 mm) malignant tumors embedded within the complex fibroglandular structure of the breast are easily detected above the background clutter. The MIST approach is shown to offer significant improvement in performance over previous UWB microwave breast cancer detection techniques based on simpler focusing schemes.