PedsQL Eosinophilic Esophagitis Module: Feasibility, Reliability, and Validity
PedsQL Eosinophilic Esophagitis Module: Feasibility, Reliability, and Validity
复制标题
DOI：
10.1097/mpg.0b013e31828f1fd2
复制
发表时间：
2013-07-01
影响因子：
2.9
通讯作者：
Varni, James W.
中科院分区：
文献类型：
--
作者：
Franciosi, James P.;Hommel, Kevin A.;Varni, James W.
目的：嗜酸性粒细胞性食管炎（EoE）是一种慢性食管炎症性疾病，有关健康相关生活质量（HRQOL）的信息很少。该研究的目的是报告 PedsQL EoE 模块的测量特性。方法：PedsQL EoE 模块由 196 名 EoE 儿科患者和 262 名 EoE 患者父母完成的多中心研究。结果：PedsQL EoE 模块量表证明了出色的可行性（缺失 0.6%-3.1%），总量表得分具有出色的组间比较可靠性（患者 0.93；家长代理） 0.94），7 个个体量表具有良好的可靠性（患者 0.75-0.87；家长代理 0.81-0.92），出色的重测可靠性（患者组内相关系数 0.88；家长组内相关系数 0.82），没有下限效应和较低的上限效应，并且大多数量表的标度成功率很高。与 PedsQL 通用核心量表的相互相关性在中等 (0.30) 到较大 (0.50) 范围内。与缓解期患者相比，活动性组织学疾病患者 (5 eos/hpf) 的 PedsQL EoE 模块评分较差（患者自我报告：63.3 vs 69.9 [P
Objective:Eosinophilic esophagitis (EoE) is a chronic esophageal inflammatory condition with a paucity of information on health-related quality of life (HRQOL). The objective of the study was to report on the measurement properties of the PedsQL EoE Module.Methods:The PedsQL EoE Module was completed in a multisite study by 196 pediatric patients with EoE and 262 parents of patients with EoE.Results:The PedsQL EoE Module scales evidenced excellent feasibility (0.6%-3.1% missing), excellent group comparison reliability across total scale scores (patient 0.93; parent proxy 0.94), good reliability for the 7 individual scales (patient 0.75-0.87; parent proxy 0.81-0.92), excellent test-retest reliability (patient intraclass correlation coefficient 0.88; parent intraclass correlation coefficient 0.82), demonstrated no floor effects and low ceiling effects, and demonstrated a high percentage of scaling success for most scales. Intercorrelations with the PedsQL Generic Core Scales were in the medium (0.30) to large (0.50) range. PedsQL EoE Module scores were worse among patients with active histologic disease (5 eos/hpf) compared with those in remission (patient self-report: 63.3 vs 69.9 [P