Bone remodelling: A signalling system for osteoclast regulation

Bone remodelling: A signalling system for osteoclast regulation
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DOI:
10.1016/s0960-9822(98)70434-8
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发表时间:
1998-09-24
期刊:
影响因子:
9.2
通讯作者:
Derynck, R
Derynck, R
中科院分区:
生物学1区
文献类型:
--
作者:
Filvaroff, E;Derynck, R

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最近发现了破骨细胞成熟的两种生理调节因子:分泌蛋白护骨素及其结合的细胞表面配体。这些蛋白质可能在控制骨吸收方面发挥重要作用,但也可能在其他组织中发挥重要作用。
Two physiological regulators of osteoclast maturation have recently been identified: the secreted protein osteoprotegerin and the cell-surface ligand to which it binds. These proteins are likely to play an important part in the control of bone resorption, but are also likely to have important roles in other tissues.