Worldwide genetic relationships of pigs as inferred from X chromosome SNPs
Worldwide genetic relationships of pigs as inferred from X chromosome SNPs
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DOI：
10.1111/j.1365-2052.2012.02374.x
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发表时间：
2013-04-01
期刊：
影响因子：
2.4
通讯作者：
Perez-Enciso, M.
中科院分区：
文献类型：
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作者：
Burgos-Paz, W.;Souza, C. A.;Perez-Enciso, M.
尽管猪X染色体具有独特的特征，但该染色体的系统地理还没有被研究过。在这里，我们对来自世界各地的312头猪的59个单核苷酸多态(SNPs)进行了基因分型，这些SNPs代表了30个国家的39个家猪品种和野猪。总体而言，广泛存在的商业品种显示出最高的杂合度，其次是非洲人和美国人。从FST和分子方差分析推断，非假常染色体(NPAR)的结构始终大于假常染色体(PAR)。我们的结果表明，种群之间的遗传关系在NPAR和PAR之间可能会有很大的差异，这突显了这样一个事实，即它们的遗传轨迹可能非常不同。与PAR相比，NPAR表现出更多的商业性遗传成分，这可能是因为人类通过引入公猪而不是母猪来选择获得高生产力参数的个体的过程。
The phylogeography of the porcine X chromosome has not been studied despite the unique characteristics of this chromosome. Here, we genotyped 59 single nucleotide polymorphisms (SNPs) in 312 pigs from around the world, representing 39 domestic breeds and wild boars in 30 countries. Overall, widespread commercial breeds showed the highest heterozygosity values, followed by African and American populations. Structuring, as inferred from FST and analysis of molecular variance, was consistently larger in the non-pseudoautosomal (NPAR) than in the pseudoautosomal regions (PAR). Our results show that genetic relationships between populations can vary widely between the NPAR and the PAR, underscoring the fact that their genetic trajectories can be quite different. NPAR showed an increased commercial-like genetic component relative to the PAR, probably because human selection processes to obtain individuals with high productive parameters were mediated by introgressing boars rather than sows.