Mixed myoclonic-absence status epilepticus in juvenile myoclonic epilepsy
Mixed myoclonic-absence status epilepticus in juvenile myoclonic epilepsy
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DOI：
10.1684/epd.2014.0719
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发表时间：
2015-03-01
影响因子：
2.3
通讯作者：
Crespel, Arielle
中科院分区：
文献类型：
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作者：
Gelisse, Philippe;Crespel, Arielle
癫痫性肌阵挛持续状态或混合性失神-肌阵挛持续状态在青少年肌阵挛性癫痫（JME）中并不常见，通常由睡眠剥夺、停药或抗癫痫药物不足引起（托马斯等人，; Crespel等人，).此类发作对苯二氮卓类或丙戊酸盐反应良好（Crespel et al.，).我们提出的视频脑电图的一个24岁的女子与JME和双相情感障碍。在停用氯硝西泮（14 mg/d）和引入奥沙西泮（200 mg/d）后5天，患者出现意识模糊状态，随后出现紧张性木僵伴面部和手臂轻微肌阵挛。EEG显示失神状态（图1、2），在IV注射氯硝西泮（1 mg）后停止（图3）。意识恢复正常[发表了视频序列和数字]。
Myoclonic status epilepticus or mixed absence-myoclonic status is uncommon in juvenile myoclonic epilepsy (JME), often precipitated by sleep deprivation, withdrawal of medication, or inadequate antiepileptic drugs (Thomas et al., ; Crespel et al., ). Such episodes respond well to benzodiazepines or valproate (Crespel et al., ). We present the video-EEG of a 24-year-old woman with JME and bipolar disorder. She had a confusional state five days after withdrawal of clonazepam (14 mg/d) and introduction of oxazepam (200 mg/d), followed by catatonic stupor with subtle myoclonus of the face and the arms. The EEG showed absence status (figures 1, 2), which stopped after IV injection of clonazepam (1 mg) (figure 3). Consciousness returned to normal [Published with video sequence and figures].