Major Habitual Dietary Patterns Are Associated with Acute Myocardial Infarction and Cardiovascular Risk Markers in a Southern European Population
Major Habitual Dietary Patterns Are Associated with Acute Myocardial Infarction and Cardiovascular Risk Markers in a Southern European Population
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DOI：
10.1016/j.jada.2010.10.042
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发表时间：
2011-02-01
影响因子：
--
通讯作者：
Lopes, Carla
中科院分区：
文献类型：
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作者：
Oliveira, Andreia;Rodriguez-Artalejo, Fernando;Lopes, Carla
在南欧，大多数饮食模式分析都依赖于使用地中海式饮食指数的先验食物方法。这些方法可能无法反映当前人口的food consumption.Objective评估的关联后验饮食模式与急性心肌梗死（AMI）和心血管疾病的危险标志物在一般成人人口的波尔图，Portugal.Design一个人口为基础的轻松控制研究进行。信息由经过培训的访谈人员收集。饮食是用一个经过验证的82项食物频率调查表进行评估的。参与者/设置病例是连续住院的非致命性AMI患者（n=820），对照是从医院的集水区选择的没有先前AMI的个体（n= 2，196）。通过多变量有限混合模型在对照组中识别。结果与健康饮食模式的妇女相比，低水果蔬菜饮食模式和红肉饮酒模式的妇女，（亦以较少进食奶类及蔬菜为特征）模式显示患急性心肌梗死的风险较高（OR 1.85，95% CI 1.01 - 3.39和OR 1.91，95% CI 1.17 - 3.12）。“红肉和酒精”模式的女性对照组也有较高的总高密度脂蛋白胆固醇比率。与具有“健康”模式的男性相比，那些具有“红肉和酒精”模式的人，与女性中发现的对应物相似，更有可能经历AMI（OR 1.98，95% CI 1.35 ~ 2.92）;具有这种模式的男性对照具有较高的舒张压和收缩压，C反应蛋白，结论：女性的饮食模式是水果和蔬菜摄入量较低，而红肉和酒精的消费量较高。（以及较低的乳制品和蔬菜）与AMI和不良心血管风险特征的风险增加相关。这些发现强调了持续推荐水果和蔬菜摄入量以及谨慎指导酒精饮料消费的重要性，这与男性和女性的健康饮食模式不太相关。美国饮食协会杂志2011;111：241-250。
Background Most dietary pattern analyses in southern Europe have relied on a priori food approaches using Mediterranean-style diet indexes. These methods may not reflect the current population's food consumption.Objective To assess the association of a posteriori dietary patterns with acute myocardial infarction (AMI) and cardiovascular risk markers in the general adult population of Porto, Portugal.Design A population-based ease-control study was conducted. Information was collected by trained interviewers. Diet was assessed with a validated 82-item food frequency questionnaire.Participants/setting Cases were patients consecutively hospitalized for an incident non-fatal AMI (n=820), and controls were individuals free of previous AMI selected from the hospitals' catchment area (n=2,196).Statistical analyses Dietary patterns, representing mutually exclusive clusters of individuals, were identified by multivariate finite mixture models among controls. Odds ratios (OR) and their 95% confidence intervals (CIs) were obtained from unconditional logistic regression, with adjustment for main confounders.Results In comparison to women with a "healthy" dietary pattern, those with a "low fruit and vegetables" pattern and a "red meat and alcohol" (also characterized by lower intake of dairy products and vegetables) pattern showed a higher risk of AMI (OR 1.85, 95% CI 1.01 to 3.39 and OR 1.91, 95% CI 1.17 to 3.12, respectively). Female controls with the "red meat and alcohol" pattern also had a higher total to high-density lipoprotein cholesterol ratio. In comparison to men with a "healthy" pattern, those with the "red meat and alcohol" pattern, similar to the counterpart found in women, were more likely to experience an AMI (OR 1.98, 95% CI 1.35 to 2.92); male controls with this pattern had higher diastolic and systolic blood pressure, C-reactive protein, and uric acid levels.Conclusions A dietary pattern with lower fruit and vegetable intakes in women, and a pattern characterized by higher consumption of red meat and alcohol (and lower of dairy products and vegetables) in both sexes, were associated with an increased risk of AMI and adverse cardiovascular risk profiles. These findings highlight the importance of sustained recommendations for fruit and vegetable intake and cautious guidance on consumption of alcoholic beverages, which clusters with less healthy dietary patterns of men and women. J Am Diet Assoc. 2011;111:241-250.