Stimulation of active sodium transport across the isolated toad bladder after injection of aldosterone to the animal.
Stimulation of active sodium transport across the isolated toad bladder after injection of aldosterone to the animal.
复制标题
向动物注射醛固酮后，刺激钠通过离体蟾蜍膀胱的主动转运。
DOI：
10.1210/endo-69-4-673
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发表时间：
1961
期刊：
影响因子：
4.8
通讯作者：
Jean Crabbé
中科院分区：
文献类型：
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作者：
Jean Crabbé
本文用短路电流技术研究了蟾蜍离体膀胱的主动钠转运。当蟾蜍被保持在蒸馏水中而不是盐水中时，发现这种制剂的钠转运更大。这种增加与较高浓度的循环醛固酮有关。这种激素被证明是由蟾蜍肾上腺组织产生的。注射醛固酮d，1 21-单乙酸酯的动物前一天处死导致刺激钠运输的孤立的膀胱，蟾蜍是否一直保持在盐水或蒸馏水中。但在给予醛固酮5天后，无论环境如何，钠转运活性都是相同的。栖息地或醛固酮注射液对离体蟾蜍膀胱主动钠转运的影响不影响制剂对加压素刺激钠转运的反应性。膀胱组织水，
Active sodium transport by the isolated urinary bladder of Bufo marinus was studied by means of the short-circuit current technique of Ussing and Zcrahn. Sodium transport by this preparation was found to be greater when toads had been maintained in distilled water rather than in saline. This increase was associated with a higher concentration of circulating aldosterone. This hormone was shown to be produced by toad adrenal tissue. Injection of aldosterone d, 1 21-monoacetate to the animals the day prior to sacrifice resulted in a stimulation of sodium transport by the isolated bladder, whether the toads had been kept in saline or in distilled water. But after administration of aldosterone for 5 days, the activity of sodium transport was the same, regardless of environment. The effect of habitat or aldosterone injections on active sodium transport by the isolated toad bladder did not influence the responsiveness of the preparation to the stimulation of sodium transport by vasopressin. Bladder tissue water,...