Chromatin-bound and free forms of poly(adenylic acid) polymerase in rat hepatic nuclei.
Chromatin-bound and free forms of poly(adenylic acid) polymerase in rat hepatic nuclei.
复制标题
大鼠肝核中染色质结合和游离形式的聚（腺苷酸）聚合酶。
作者：
S. Jacob;F. J. Roe;K. Rose
分离的大鼠肝核显示出含有两种不同生理活性形式的聚腺苷酸聚合酶。一种形式与染色质部分相关，并且依赖于内源性 RNA（可能是 mRNA）。另一种活性以“游离”形式定位于核液中，并被外源添加的聚腺苷酸刺激了近 30-40 倍。分离的核仁缺乏显着的聚腺苷酸合成活性。
Isolated rat hepatic nuclei were shown to contain poly(A) polymerase in two distinct physiologically active forms. One form was associated with the chromatin fraction and was dependent on endogenous RNA, presumably mRNA. The other activity was localized in the nuclear sap in a 'free' form and was stimulated almost 30-40-fold by exogenously added poly(A). Isolated nucleoli were devoid of significant poly(A)-synthesizing activity.