User-friendly chemical patterning with digital light projection polymer brush photolithography
User-friendly chemical patterning with digital light projection polymer brush photolithography
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DOI：
10.1016/j.eurpolymj.2021.110652
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发表时间：
2021-07
影响因子：
6
通讯作者：
Michele Fromel;Raymond L. Crisci;Chinmay S. Sankhe;D. R. Hickey;T. Tighe;Esther W. Gomez;Christian W. Pester
中科院分区：
文献类型：
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作者：
Michele Fromel;Raymond L. Crisci;Chinmay S. Sankhe;D. R. Hickey;T. Tighe;Esther W. Gomez;Christian W. Pester
图案化聚合物涂层广泛适用于生物工程的所有领域：抗生物污染，受控蛋白质吸附，引导细胞生长等等。这一贡献描述了一个强大的地形和化学图案化平台，结合了耐氧光介导聚合的LED数字光投影仪设计先进的表面上微米尺度和温和的环境条件。这种方法的用户友好性旨在将基于表面束缚聚合物的复杂化学图案化能力带入非专家手中，并使生物工程中与图案化表面相关的基础和应用研究成为可能。
Patterned polymeric coatings are broadly relevant for all areas of bioengineering: anti-biofouling, controlled protein adsorption, guided cell growth, and many more. This contribution describes a robust topographical and chemical patterning platform that combines an LED digital light projector with oxygen-tolerant light-mediated polymerization to design advanced surfaces on the micron scale and in mild ambient conditions. The user-friendly nature of this approach is targeted towards bringing complex chemical patterning abilities based on surface-tethered polymers into the hands of non-experts and enabling both fundamental and applied studies related to patterned surfaces in bioengineering.