A study of the xenoantigenicity of adult pig islets cells
A study of the xenoantigenicity of adult pig islets cells
复制标题
成年猪胰岛细胞异种抗原性的研究
DOI：
10.1111/j.1399-3089.2004.00121.x
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发表时间：
2004
影响因子：
3.9
通讯作者：
R. Shirakura
中科院分区：
文献类型：
--
作者：
H. Komoda;S. Miyagawa;T. Kubo;E. Kitano;H. Kitamura;T. Omori;Toshinori Ito;H. Matsuda;R. Shirakura
摘要：背景：猪胰腺被认为是I型糖尿病患者异种胰岛移植最合适的胰岛来源。本研究的目的是评估猪胰岛的抗原性，包括α α1‐3Galβ1‐4GlcNAc‐R （α‐Gal）和Hanganutziu‐Deicher （H‐D）抗原，以及参与人类补体激活的途径。
Abstract: Background: The pig pancreas is considered to be the most suitable source of islets for xenotransplantation into patients with type I diabetes. The purpose of this study was to assess the antigenicity of pig islets, including the Galα1‐3Galβ1‐4GlcNAc‐R (the α‐Gal) and Hanganutziu‐Deicher (H‐D) antigens, and the pathway involved in human complement activation.
影响因子：
56.9
作者：
C. Phelps;C. Koike;T. Vaught;J. Boone;K. Wells;Shu-Hung Chen;S. Ball;S. Specht;I. Polejaeva;Jeff A. Monahan;P. Jobst;Sugandha B. Sharma;Ashley E. Lamborn;A. S. Garst;M. Moore;A. Demetris;W. Rudert;R. Bottino;S. Bertera;M. Trucco;T. Starzl;Yifan Dai;D. Ayares
通讯作者：
C. Phelps;C. Koike;T. Vaught;J. Boone;K. Wells;Shu-Hung Chen;S. Ball;S. Specht;I. Polejaeva;Jeff A. Monahan;P. Jobst;Sugandha B. Sharma;Ashley E. Lamborn;A. S. Garst;M. Moore;A. Demetris;W. Rudert;R. Bottino;S. Bertera;M. Trucco;T. Starzl;Yifan Dai;D. Ayares