Self-Assembled Peptide Nanofibers

Self-Assembled Peptide Nanofibers
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DOI:
10.1007/12_2008_169
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发表时间:
2008
影响因子:
--
通讯作者:
N. Higashi;T. Koga
N. Higashi;T. Koga
中科院分区:
化学4区
文献类型:
--
作者:
N. Higashi;T. Koga

文献摘要

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分子自组装是一种正在探索的制备新型超分子纳米结构的有效方法 和仿生纳米材料。本文主要介绍了近年来有关自组装的研究进展 的从头设计的人工肽和肽模拟物到peptidomimetics结构,特别是对 开发了一种新型的软材料。这些嵌入式体系结构不仅具有潜在的用途, 在生物医学应用中,例如用于组织工程和生物矿化的3D基质支架,但是 也可用于纳米技术,例如纳米模板和尺寸调节功能纳米物体。
Molecular self-assembly is a powerful approach being explored for novel supramolecular nanostructures and bio-inspired nanomaterials. In this article, we focus on recent research concerning the self-assembly of de novo designed artificial peptides and peptidomimetics into nanofiber structures, specifically towards developing a new class of soft-materials. These nanofiber architectures have potential use not only in biomedical applications, such as 3D-matrix scaffolds for tissue engineering and biomineralization, but also in nanotechnology such as nano-templates and dimension-regulated functional nano-objects.