Self-gated golden-angle spiral 4D flow MRI
Self-gated golden-angle spiral 4D flow MRI
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DOI：
10.1002/mrm.27085
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发表时间：
2018-09-01
影响因子：
3.3
通讯作者：
Giese, Daniel
中科院分区：
文献类型：
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作者：
Bastkowski, Rene;Weiss, Kilian;Giese, Daniel
目的4D血流磁共振成像(MRI)在心血管领域的应用最近在临床可行性方面取得了很大进展。同时补偿心脏和呼吸运动的需要仍然是临床广泛应用的一个挑战。特别是，通过门控方法处理的呼吸运动可能会导致不可预测的长时间扫描。目前的工作提出了一种时间效率高的自门4D血流序列，该序列利用高达100%的采集数据，并在可预测的扫描时间运行。方法在10名志愿者身上实现并测试自门控黄金角螺旋4D血流序列。数据被追溯地绑定到呼吸和心脏状态，并使用共轭梯度敏感性编码重建。评估主动脉的净血流曲线、每搏输出量和峰值血流，并与传统的笛卡尔四维血流序列进行比较。此外，还比较了从50%到100%的自门4D血流数据重建的流量。结果所有志愿者的呼吸和心脏运动的自门信号都被提取出来。血流量与标准笛卡尔扫描结果一致。每搏输出量和峰值流量的平均差值分别为7.611.5和4.0+/-79.9mL/S。通过回溯提高呼吸导航效率，减少采集时间(15：06-07：33分钟)，50%的采集数据足以测量每搏输出量，误差在9.6mL以下。结论在可预测的扫描时间获取呼吸和心脏自门4D血流数据是可行的。Magn Reson Med 80：904-913,2018。(C)2018年国际核磁共振医学学会。
PurposeThe acquisition of 4D flow magnetic resonance imaging (MRI) in cardiovascular applications has recently made large progress toward clinical feasibility. The need for simultaneous compensation of cardiac and breathing motion still poses a challenge for widespread clinical use. Especially, breathing motion, addressed by gating approaches, can lead to unpredictable and long scan times. The current work proposes a time-efficient self-gated 4D flow sequence that exploits up to 100% of the acquired data and operates at a predictable scan time.MethodsA self-gated golden-angle spiral 4D flow sequence was implemented and tested in 10 volunteers. Data were retrospectively binned into respiratory and cardiac states and reconstructed using a conjugate-gradient sensitivity encoding reconstruction. Net flow curves, stroke volumes, and peak flow in the aorta were evaluated and compared to a conventional Cartesian 4D flow sequence. Additionally, flow quantities reconstructed from 50% to 100% of the self-gated 4D flow data were compared.ResultsSelf-gating signals for respiratory and cardiac motion were extracted for all volunteers. Flow quantities were in agreement with the standard Cartesian scan. Mean differences in stroke volumes and peak flow of 7.611.5 and 4.0 +/- 79.9mL/s were obtained, respectively. By retrospectively increasing breathing navigator efficiency while decreasing acquisition times (15:06-07:33 minutes), 50% of the acquired data were sufficient to measure stroke volumes with errors under 9.6mL.ConclusionThe feasibility to acquire respiratory and cardiac self-gated 4D flow data at a predictable scan time was demonstrated. Magn Reson Med 80:904-913, 2018. (c) 2018 International Society for Magnetic Resonance in Medicine.