Single versus multiple cervical dilation by osmotic dilator before induction of labor for second-trimester abortion

Single versus multiple cervical dilation by osmotic dilator before induction of labor for second-trimester abortion
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中期流产引产前使用渗透扩张器进行单次宫颈扩张与多次宫颈扩张的比较

DOI:
10.1111/jog.13930
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发表时间:
2019
期刊:
J Obstet Gynaecol Res
影响因子:
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通讯作者:
T.
T.
中科院分区:
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文献类型:
--
作者:
Lee;M. Mimura;K. Endoh;M. Kawanishi;Y. Miyake;T. Kakigano;A. Takiuchi;T. Matsuzaki;S. Tomimatsu;T. Kimura;T.

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Aim在这项研究中,我们的目的是调查是否有一个显着的预后差异单和多次宫颈扩张时,诱导中期pregnancy abortion.MethodsWe进行了回顾性分析,238名孕妇谁接受终止妊娠在12-21周的妊娠在大坂大学医院在日本大坂,2010年1月至2018年5月。终止妊娠进行阴道给药的1毫克吉美前列素每3小时,每天多达5个剂量后,宫颈扩张lamicel.ResultsThe妇女分为两组:191名妇女的分娩时间<24小时,而47分娩时间>24小时。两组相比,两组间的血小板数量(分别为88 [46.1%]和32 [68.1%])和板层交换± SD(<24 h分别为1.9 ± 0.67和>24 h分别为2.4 ± 0.87)存在显著差异。此外,我们还比较了单次更换子宫片的产妇与更换≥2次子宫片的产妇的预后,但在分娩时间>24 h的人数和使用吉美前列素的人数方面没有显著差异。结论初产妇是人工流产延迟分娩的危险因素。然而,增加更换的层片数量并不能显著缩短输送时间;因此,应尽可能少地进行。
AimIn this study, we aimed to investigate whether there was a significant prognostic difference between single and multiple cervical dilations when inducing second‐trimester abortion.MethodsWe conducted a retrospective review of 238 pregnant women who underwent termination of pregnancy at 12–21 weeks of gestation at Osaka University Hospital in Osaka, Japan, between January 2010 and May 2018. Termination of pregnancy was performed by vaginal administration of 1 mg gemeprost every 3 h for up to five doses per day after uterine cervical dilation using lamicel.ResultsThe women were categorized into two groups: 191 women had a delivery time of <24 h, whereas 47 had delivery times >24 h. Contrasting the groups, there were significant differences with regard to numbers of primiparas (88 [46.1%] and 32 [68.1%], respectively) and lamicel exchanges ± SD (1.9 ± 0.67 for <24 h and 2.4 ± 0.87 for >24 h, respectively). Additionally, we compared the prognosis of primiparas that received just a single lamicel with that of primiparas that had ≥2 exchanged, but no significant differences were noted in the number of patients with a delivery time of >24 h and the number of used gemeprost.ConclusionPrimipara is a risk factor for delayed delivery time of induced abortion. However, increasing the number of exchanged lamicel did not significantly reduce the delivery time; therefore, it should be performed as minimally as possible.