A CONTINUOUS-FLOW INPUT FUNCTION DETECTOR FOR H-2 O-15 BLOOD-FLOW STUDIES IN POSITRON EMISSION TOMOGRAPHY

A CONTINUOUS-FLOW INPUT FUNCTION DETECTOR FOR H-2 O-15 BLOOD-FLOW STUDIES IN POSITRON EMISSION TOMOGRAPHY
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DOI:
10.1109/tns.1986.4337162
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发表时间:
1986-02-01
影响因子:
1.8
通讯作者:
KOEPPE, RA
KOEPPE, RA
中科院分区:
工程技术3区
文献类型:
--
作者:
HUTCHINS, GD;HICHWA, RD;KOEPPE, RA

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塑料闪烁体探测系统已被开发用于测量动脉血H2 15 O浓度的正电子发射断层扫描(PET)局部脑血流(lCBF)的研究。该系统使用蠕动泵从桡动脉连续抽取动脉血,通过塑料闪烁体检测氧-15正电子。为了纠正由于泵管中的层流而导致的动脉血液曲线形状的涂抹,开发了一种去卷积技术。
A plastic scintillator detection system has been developed for the measurement of arterial blood H2 15O concentrations in positron emission tomographic (PET) local cerebral blood flow (lCBF) studies. The system uses a peristaltic pump to continually pull arterial blood from a radial artery through the plastic scintillator for the detection of the oxygen-15 positrons. To correct for the smearing of the arterial blood curve shape due to laminar flow in the pump tubing, a deconvolution technique has been developed.