Mucinous Adenocarcinoma of the Parotid Gland
Mucinous Adenocarcinoma of the Parotid Gland
复制标题
腮腺粘液性腺癌
DOI：
10.1159/000331300
复制
发表时间：
1999
期刊：
影响因子：
1.8
通讯作者：
J. Eichhorn
中科院分区：
文献类型：
--
作者：
R. Tambouret;R. Yantiss;R. Kirby;J. Eichhorn
背景
粘液腺癌很少作为腮腺内的原发肿瘤出现，并且仅描述了该肿瘤的组织学特征。
案例
一名 72 岁男性的右腮腺在六周内出现了一个 4 厘米的坚硬肿块。计算机断层扫描显示该肿块呈囊性，细针抽吸活检显示该肿块呈单形、中度非典型细胞，有单个细胞也有成簇细胞，伴有丰富的粘液物质和局灶性坏死。肿瘤细胞具有偏心的细胞核、突出的核仁和偶尔的细胞质空泡化。存在一些双核和多核肿瘤细胞。切除腺体的组织学切片显示粘液性腺癌。转移性检查结果呈阴性。细胞学鉴别诊断包括产生粘蛋白或粘液基质的其他原发性腮腺肿瘤和转移性粘液腺癌。
结论
据我们所知，这是对原发于腮腺的粘液性腺癌的第一个细胞学描述。
BACKGROUND
Mucinous adenocarcinoma rarely arises as a primary tumor within the parotid gland, and only the histologic features of this tumor have been described.
CASE
A 4-cm, firm mass arose in the right parotid gland of a 72-year-old male over a six-week period. Cystic on computed tomography, the mass, on fine needle aspiration biopsy, yielded monomorphic, moderately atypical cells, both single and clustered, associated with abundant mucoid material and focal necrosis. Tumor cells had eccentric nuclei, prominent nucleoli and occasional cytoplasmic vacuolization. A few binucleated and multinucleated tumor cells were present. Histologic sections of the resected gland showed mucinous adenocarcinoma. A metastatic workup was negative. The differential diagnoses on cytology included other primary tumors of the parotid gland producing mucin or a mucoid matrix and metastatic mucinous adenocarcinomas.
CONCLUSION
To our knowledge, this is the first cytologic description of mucinous adenocarcinoma, primary in the parotid gland.