Socio-demographic heterogeneity in the prevalence of COVID-19 during lockdown is associated with ethnicity and household size: Results from an observational cohort study
Socio-demographic heterogeneity in the prevalence of COVID-19 during lockdown is associated with ethnicity and household size: Results from an observational cohort study
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DOI：
10.1016/j.eclinm.2020.100466
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发表时间：
2020-08-01
影响因子：
15.1
通讯作者：
Pareek, Manish
中科院分区：
文献类型：
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作者：
Martin, Christopher A.;Jenkins, David R.;Pareek, Manish
背景：越来越多的证据表明，COVID-19在少数民族群体中造成了不良后果。然而，关于种族和家庭规模对获得性SARS-CoV-2感染的影响知之甚少。方法：我们在莱斯特（英国）进行了一项回顾性队列研究，研究对象是2020年3月1日至4月28日在莱斯特NHS信托大学医院接受COVID-19聚合酶链反应（PCR）检测的所有个体。我们使用逻辑回归来确定社会人口统计学，临床和时间因素与SARS-CoV-2 PCR阳性之前/之后lockdown.Findings相关：971/4051（24.0%）疑似COVID-19患者被发现为SARS-CoV-2 PCR阳性。PCR阳性在少数民族背景的个体中比他们的白色同伴更常见（白色20.0%，南亚人37.5%，黑人36.1%，其他32.2%; p
Background: Accumulating evidence indicates that COVID-19 causes adverse outcomes in ethnic minority groups. However, little is known about the impact of ethnicity and household size on acquiring infection with SARS-CoV-2.Methods: We undertook a retrospective cohort study, in Leicester (UK), of all individuals assessed for COVID-19 with polymerase chain reaction (PCR) testing at University Hospitals of Leicester NHS Trust between 1st March and 28th April 2020. We used logistic regression to identify sociodemographic, clinical and temporal factors associated with SARS-CoV-2 PCR positivity before/after lockdown.Findings: 971/4051 (24.0%) patients with suspected COVID-19 were found to be PCR positive for SARS-CoV-2. PCR positivity was more common amongst individuals from ethnic minortiy backgrounds than their White counterparts (White 20.0%, South Asian 37.5%, Black 36.1%, Other 32.2%; p