Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control.
Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control.
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粘液铜绿假单胞菌中的藻酸盐合成：参与控制的染色体位点。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
J. Govan
中科院分区：
文献类型：
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作者：
J. Fyfe;J. Govan
在体外或体内分离的铜绿假单胞菌的粘液变异体可以根据藻酸盐是否在化学定义的培养基上产生而分为两个表型组。在FP2介导的平板配对中，粘液型菌株作为供体时，重组频率比非粘液型亲本低。粘液特性(MUC)由选择用于染色体标记His-5075+或Cys-5605+遗传的一定比例的重组子共同遗传。用黏液受体或黏液供体携带质粒R68.45的进一步实验结果表明，控制铜绿假单胞菌藻酸盐的产生至少涉及一个染色体位点。
Mucoid variants of Pseudomonas aeruginosa isolated in vitro or in vivo could be classified into two phenotypic groups based on whether alginate was produced on a chemically defined medium. Mucoid strains yielded lowe recombination frequencies than the non-mucoid parent when used as donors in FP2-mediated plate matings. The mucoid characteristic (muc) was co-inherited by a proportion of recombinants selected for the inheritance of chromosomal markers his-5075+ or cys-5605+. The results of further experiments using either a mucoid recipient or a mucoid donor carrying plasmid R68.45 suggested that the control of alginate production in P. aeruginosa involves at least one chromosomal locus.