Placebo Analgesia in Rodents: Current and Future Research.

Placebo Analgesia in Rodents: Current and Future Research.
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DOI:
10.1016/bs.irn.2018.02.001
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发表时间:
2018
影响因子:
--
通讯作者:
Colloca L
Colloca L
中科院分区:
医学3区
文献类型:
--
作者:
Keller A;Akintola T;Colloca L

文献摘要

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在动物疼痛模型中的安慰剂效应的研究受到的关注比人类研究少。这可能与许多困难有关,包括动物缺乏使用语言和口头建立期望的能力,动物不能报告和评估它们经历疼痛的程度,以及当前疼痛模型的不足。在这里,我们描述了已经发表的相对较少的研究,传达了这项研究的机会和兴奋。我们批判性地讨论了陷阱和局限性,希望这将推动未来的动物安慰剂相关的研究。
The investigation of placebo effects in animal pain models has received less attention than human research. This may be related to a number of difficulties, including the fact that animals lack the ability to use language and establish expectancies verbally, that animals cannot report and rate the extent to which they experience pain, and the inadequacy of current models of pain. Here, we describe the relatively small number of studies that have been published, communicating the opportunities and excitement of this research. We critically discuss pitfalls and limitations with the hope that this will advance future animal placebo-related research.