Cellular and molecular mechanisms involved in branching morphogenesis of the Drosophila tracheal system
Cellular and molecular mechanisms involved in branching morphogenesis of the Drosophila tracheal system
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DOI：
10.1152/japplphysiol.00435.2004
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发表时间：
2004-12-01
影响因子：
3.3
通讯作者：
Affolter, M
中科院分区：
文献类型：
--
作者：
Cabernard, C;Neumann, M;Affolter, M
Recent comparative studies have shown that, in many instances, the genetic network underlying the development of distinct organ systems is similar in invertebrate and vertebrate organisms. Genetically well-characterized, simple invertebrate model systems, such as Caenorhabditis elegans and Drosophila melanogaster, can thus provide useful insight for understanding more complex organ systems in vertebrates. Here, we summarize recent progress in the genetic analysis of tracheal development in Drosophila and compare the results to studies aimed at a better understanding of lung development in mouse and man. Clearly, both striking similarities and important differences are apparent, but it might still be too early to conclude whether the former or the latter prevail.
