Effect of continuous pressure on histopathological changes in denture-supporting tissues
Effect of continuous pressure on histopathological changes in denture-supporting tissues
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DOI：
10.1046/j.1365-2842.1997.00443.x
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发表时间：
1997-01-01
影响因子：
2.9
通讯作者：
Minagi, S
中科院分区：
文献类型：
--
作者：
Mori, S;Sato, T;Minagi, S
通过对实验性义齿基托施加持续压力，研究了义齿支持组织的组织病理学变化。实验义齿设计成向大鼠磨牙区腭部施加持续压力（1.5、3.4或4.9kPa）。观察了持续压力引起的组织学变化，并估计了压力的强度。义齿基托下组织病理学改变与持续压力强度之间存在高度相关性。在4.9和3.4kPa组中，持续机械压力引起骨吸收，在1.5kPa组中，没有观察到骨吸收的证据。义齿基托下的上皮和粘膜固有层，这是由连续压力压缩，恢复组织病理学取决于骨吸收引起的压力下降，没有观察到定量的恢复吸收的骨组织。持续压力未引起炎症变化。从本研究中观察到的组织病理学结果来看，持续压力诱导的骨吸收存在阈值的可能性。
The histopathological changes in denture-supporting tissues were studied in relation to continuous pressure exerted through an experimental denture base. The experimental dentures were designed to load continuous pressures (1.5, 3.4 or 4.9 kPa) to the palate of molar region of rat. Histopathological changes caused by the continuous pressure were observed, and the intensity of the pressure was also estimated. A high correlation was observed between the histopathological changes under the denture base and the intensity of the continuous pressure. In groups exposed to 4.9 and 3.4 kPa, the continuous mechanical pressure caused bone resorption; in 1.5 kPa group, no evidence of bone resorption was observed. The epithelium and lamina propria mucosa under the denture base, which were compressed by the continuous pressure, recovered histopathologically depending on the decrease of the pressure caused by bone resorption; no quantitative recovery of the absorbed bone tissue was observed. No inflammatory change was induced by the continuous pressure. From the histopathological results observed in this study, the possibility of the existence of a threshold for bone resorption induced by continuous pressure was suggested.