EXOGENOUS HYALURONATE AS AN ADJUNCT IN THE PREVENTION OF ADHESIONS AFTER FLEXOR TENDON SURGERY - A CONTROLLED CLINICAL-TRIAL
EXOGENOUS HYALURONATE AS AN ADJUNCT IN THE PREVENTION OF ADHESIONS AFTER FLEXOR TENDON SURGERY - A CONTROLLED CLINICAL-TRIAL
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DOI：
10.1016/0363-5023(92)90128-c
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发表时间：
1992-01-01
影响因子：
1.9
通讯作者：
HAGBERG, L
中科院分区：
文献类型：
--
作者：
HAGBERG, L
限制肌腱滑动的术后粘连是II区肌腱修复和移植失败的主要原因。一些实验报告称，外源性应用透明质酸钠有助于防止此类粘连的形成。在一项前瞻性、双盲、随机、开放治疗对照的临床研究中，120指肌腱缝合或肌腱移植完成后，将透明质酸钠或生理盐水注入肌腱鞘内。透明质酸钠在随访时对总的主动运动没有统计学意义的影响。
Postoperative adhesions that restrict tendon gliding are a major cause of failure after tendon repair and grafting in zone II. Several experimental reports have claimed that exogenously administered sodium hyaluronate helps to prevent the formation of such adhesions. In a prospective double-blind, randomized, clinical study with open therapeutic control sodium hyaluronate or physiologic saline solution was injected into the tendon sheath after completion of tenorrhaphy or tendon grafting in 120 digits. Sodium hyaluronate had no statistically significant effect as evaluated on total active motion at follow-up.