High affective risk perception is associated with more lung cancer-specific distress in CT screening for lung cancer
High affective risk perception is associated with more lung cancer-specific distress in CT screening for lung cancer
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DOI：
10.1016/j.lungcan.2008.03.029
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发表时间：
2008-12-01
期刊：
影响因子：
5.3
通讯作者：
de Koning, Harry J.
中科院分区：
文献类型：
--
作者：
Bunge, Eveline M.;van den Bergh, Karien A. M.;de Koning, Harry J.
癌症筛查可能会造成痛苦。认为自己患癌症风险较高的人可能更容易遭受痛苦。本研究评估了肺癌计算机断层扫描 (CT) 筛查试验中具有患肺癌高情感风险感知的参与者在 CT 筛查期间是否具有较高水平的肺癌特异性痛苦。此外，我们还评估了参与者在筛查后 6 个月与筛查前 1 天相比，是否意识到自己罹患肺癌的风险存在差异。 NELSON 试验（荷兰-比利时高危受试者肺癌筛查随机对照试验）的总共 351 名后续参与者被随机分配到筛查组，并被要求在筛查前 1 天和筛查后 6 个月填写调查问卷。评估了肺癌特异性困扰（事件量表（IES）的影响）、一般健康相关生活质量（SF-12）和情感风险感知。筛选前一天，具有高情感风险感知的参与者 (n=47/321, 14.6%) 的 IES 中值分数显着高于 (即更差) 具有低情感风险感知的参与者 (11.5 vs. 2.0, p)
Screening for cancer can cause distress. People who perceive their risk of cancer as high may be more vulnerable to distress. This study evaluated whether participants of a lung cancer Computed Tomography (CT) screening trial with a high affective risk perception of developing lung cancer had a higher level of lung cancer-specific distress during CT screening. Furthermore, we evaluated whether participants perceived their risk of developing tung cancer differentty 6 months after screening compared with 1 day before screening. A total of 351 subsequent participants of the NELSON-trial (Dutch-Belgian randomized controlled trial for lung cancer screening in high-risk subjects), who were randomized to the screen arm, were asked to fill in questionnaires 1 day before and 6 months after screening. Lung cancer-specific distress (impact of Event Scale (IES)), generic health-related quality of life (SF-12) and affective risk perception were assessed. One day before screening, the participants with a high affective risk perception (n=47/321, 14.6%) had significantly higher (i.e., worse) median IES scores than participants with a tow affective risk perception (11.5 vs. 2.0, p