Triple positivity of HBsAg, anti-HCV antibody, and HIV and their influence on CD4+lymphocyte levels in the highly HIV infected population of Abeokuta, Nigeria

Triple positivity of HBsAg, anti-HCV antibody, and HIV and their influence on CD4+lymphocyte levels in the highly HIV infected population of Abeokuta, Nigeria
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DOI:
10.4314/ahs.v15i3.4
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发表时间:
2015-01-01
影响因子:
1
通讯作者:
Okonko, Iheanyi Omezuruike
Okonko, Iheanyi Omezuruike
中科院分区:
医学4区
文献类型:
--
作者:
Ogwu-Richard, Sandra Olukemi;Ojo, David Ajiboye;Okonko, Iheanyi Omezuruike

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目的:研究尼日利亚Abeokuta地区HIV感染者中HIV、HBs Ag和丙型肝炎病毒(HCV)三重阳性的情况,并明确随着尼日利亚抗逆转录病毒治疗的进步,这三重感染对HIV感染者外周血中CD4+细胞的影响。结果:经统计学处理,差异有统计学意义(P<0.05)。
Background: Few studies exist on hospital-based seroprevalence of triple positivity of HIV/HBV/HCV in Nigeria.Objectives: The study aimed at determining the triple positivity of HIV, HBsAg and HCV among HIV-infected individuals in Abeokuta, Nigeria and defining the influence of these triple infections on CD4+ counts of HIV-infected individuals as antiretroviral therapy improves in Nigeria.Methods: Enumeration of CD4+ levels in 183 HIV-infected persons was done with Partec Flow Cytometer. Seropositivity of HBsAg and anti-HCV antibody was detected with rapid kits.Results: From the result obtained, significance variance (p