Facile fabrication of reduction-responsive nanocarriers for controlled drug release
Facile fabrication of reduction-responsive nanocarriers for controlled drug release
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DOI：
10.1039/c4py00577e
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发表时间：
2014-07
影响因子：
4.6
通讯作者：
Rui Sun;Qiaojie Luo;Chen Gao;Ying Wang;Lilong Gao;H. Du;Ying Huang;Xiaodong Li;Zhi-quan Shen;Weipu Zhu
中科院分区：
文献类型：
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作者：
Rui Sun;Qiaojie Luo;Chen Gao;Ying Wang;Lilong Gao;H. Du;Ying Huang;Xiaodong Li;Zhi-quan Shen;Weipu Zhu
以二羟基聚乙二醇、1,4-丁二醇和巯基琥珀酸为原料，通过“一锅”缩聚制备了一种含多硫醇的两亲性多嵌段聚醚酯，可用于制备具有还原反应的核交联胶束，用于药物控释。
An amphiphilic multiblock poly(ether–ester) containing multiple thiols was facilely synthesized by “one-pot” polycondensation of dihydroxyl poly(ethylene glycol), 1,4-butanediol and mercaptosuccinic acid, which could be used to fabricate reduction-responsive core-crosslinked micelles for controlled drug release.