Synthesis, Characterization, and Pesticidal Activity of Emamectin Benzoate Nanoformulations against Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae)
Synthesis, Characterization, and Pesticidal Activity of Emamectin Benzoate Nanoformulations against Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae)
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DOI：
10.3390/molecules24152801
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发表时间：
2019-08-01
期刊：
影响因子：
4.6
通讯作者：
Shi, Zuhua
中科院分区：
文献类型：
--
作者：
Elabasy, Asem;Shoaib, Ali;Shi, Zuhua
利用纳米技术开发农药新剂型被认为是提高农药在各种气候条件下的效率、安全性和光稳定性的一种可能选择。本研究以纤维素纳米晶体（CNCs）和二氧化硅纳米颗粒（SNPs）为载体，采用冷冻干燥法制备了两种新型甲氨基阿维菌素苯甲酸盐（EMB）纳米制剂。采用场发射扫描电子显微镜（FE-SEM）、透射电子显微镜（TEM）、X射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、热重分析（TGA）和动态光散射（DLS）对合成的纳米制剂进行了检查。结果表明，SNPs和CNCs对EMB的负载率分别为43.31%和15.04%（w/w），并能有效地保护EMB免受紫外光照射。EMB + SNP、EMB + CNCs和EMB商业制剂对番茄粉蚧的LC 50值分别为0.01、0.05和0.31 μ g/mL，表明两种NF比EMB商业制剂更有效。这项工作旨在开发新的纳米载体，用于农药在植物保护中的潜在应用，这将减少农药的推荐剂量，从而减少食品和环境中的农药残留量。
Using nanotechnology to develop new formulations of pesticides is considered a possible option in enhancing the efficiency, safety, and photostability of pesticides under various climatic conditions. In the present study, two novel nanoformulations (NFs) were successfully prepared based on nano-delivery systems for emamectin benzoate (EMB) by loading it on cellulose nanocrystals (CNCs) and silicon dioxide nanoparticles (SNPs) as carriers through a freeze-drying method. The synthesized nanoformulations were examined using field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and dynamic light scattering (DLS). The results showed that SNPs and CNCs had a loading efficiency of 43.31% and 15.04% (w/w) for EMB, respectively, and could effectively protect EMB from photolysis under UV radiation. The LC50 values for EMB + SNPs, EMB + CNCs, and EMB commercial formulation against Phenacoccus solenopsis were 0.01, 0.05, and 0.31 mu g/mL, respectively, indicating that both NFs were more effective than the EMB commercial formulation. This work seeks to develop new nano-carriers for potential applications of pesticides in plant protection, which will reduce the recommended dose of pesticides and thereby decrease the amount of pesticide residue in food and the environment.