FIMRe: Federation of International Mouse Resources: Global networking of resource centers
FIMRe: Federation of International Mouse Resources: Global networking of resource centers
复制标题
DOI：
10.1007/s00335-006-0001-2
复制
发表时间：
2006-05-01
期刊：
影响因子：
2.5
通讯作者：
Davisson, Muriel
中科院分区：
文献类型：
--
作者：
Davisson, Muriel
17个国家资助的创始研究资源中心来自参与国，并选举杰克逊实验室的Barbara Knowles博士担任董事会主席。诺尔斯博士和四名副主席将担任管理机构，他们分别来自拥有储存库的大洲。FIMRe成员于2005年10月在马里兰州贝塞斯达正式成立了该组织。FIMRe的使命是协调资源中心，促进全球范围内获取鼠标资源。FIMRe S的目标是促进使用人类和动物发育和疾病的小鼠模型，为世界各地的研究人员造福。在实践中，FIMRe的目的将是协调存储库，以更有效地共享小鼠品系的存档和分配，如冷冻保存的胚胎和配子、ES细胞系和活的繁育种群。具体目标是根据全球研究需求协调有价值的转基因小鼠和ES细胞系的存档在所有资源中心建立一致和尽可能高质量的动物健康标准提供突变的基因验证和遗传背景的质量控制合作确保存档品系在全球范围内的快速分布并提供资源培训使研究人员能够利用现有的小鼠资源FIMRe S总目标是确保可获得性、保证质量、促进共享和保存转基因小鼠，并向全球生物医学研究界传播信息、附属资源和使用它们的专业知识。所有FIMRE资源中心保存的菌株被列入国际老鼠品系资源(http://www.)IMSR。Org)，以及在它们各自的网站上。
the 17 nationally funded founding research resource centers from the participating countries and elected Dr. Barbara Knowles from The Jackson Laboratory to chair the board. Dr. Knowles and four vice chairpersons, one from each of the continents that have repositories, will serve as the governing body. FIMRe members formalized the organization in Bethesda, Maryland, in October 2005. The mission of FIMRe is ‘‘To coordinate resource centers to facilitate worldwide access to mouse resources.’’FIMReÕs goal is to facilitate the use of mouse models of human and animal development and disease for the benefit of researchers around the world. In practice, the purpose of FIMRe will be to coordinate repositories to share more effectively the archiving and distribution of strains of mice as cryopreserved embryos and gametes, ES cell lines, and live breeding stock. The specific goals are to coordinate the archiving of valuable genetically defined mice and ES cell lines in line with global research demand establish consistent and the highest possible quality animal health standards in all resource centers provide genetic verification of the mutations and quality control for genetic background collaborate to ensure rapid distribution of archived strains worldwide and provide resource training to enable researchers to use existing mouse resourcesFIMReÕs overall goal is to ensure availability, assure quality, promote sharing and preservation of genetically defined mice, and disseminate information, affiliated resources, and expertise in their use to the global biomedical research community. Strains held at all the FIMRe resource centers are listed in the International Mouse Strain Resource (IMSR)(http://www. imsr. org), and at their individual web sites.