Measuring ipsilateral silent period: Effects of muscle contraction levels and quantification methods
Measuring ipsilateral silent period: Effects of muscle contraction levels and quantification methods
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DOI：
10.1016/j.brainres.2017.08.015
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发表时间：
2017-11-01
期刊：
影响因子：
2.9
通讯作者：
Fisher, Beth E.
中科院分区：
文献类型：
--
作者：
Kuo, Yi-Ling;Dubuc, Tobin;Fisher, Beth E.
同侧沉默期（iSP）是一个经常测量的指标，纵裂抑制。然而，各研究所用的方法不一致，也有差异。我们研究了实现iSP测量一致性的最佳收缩水平和量化方法。25名健康成年人在三种条件下（30%，50%和100%的最大自主收缩）进行右等长拇指外展，同时经颅磁刺激施加在拇短展肌的初级运动皮层代表区域。通过iSP持续时间、iSP面积和标准化iSP定量iSP。通过方差齐性检验和变异系数确定测量一致性。当通过iSP持续时间和标准化iSP测量时，所有收缩水平的iSP是一致的。标准化iSP显示最小的测量变异性。我们建议，未来的调查研究半球间抑制使用标准化的iSP测量的一致性和能力，比较研究结果。(C)2017爱思唯尔B.V.保留所有权利。
Ipsilateral silent period (iSP) is a frequently measured index of interhemispheric inhibition. However, the methodology used across studies has been inconsistent and variable. We investigated the optimal contraction level and quantification methods for achieving iSP measurement consistency. Twenty-five healthy adults performed right isometric thumb abduction under three conditions (30%, 50%, and 100% of maximal voluntary contraction) while transcranial magnetic stimulation was applied over the primary motor cortex representational area of the abductor pollicis brevis. iSP was quantified by: iSP duration, iSP area and normalized iSP. Measurement consistency was determined by the homogeneity of variance test and by the coefficient of variation. iSP was consistent across all contraction levels when measured by iSP duration and normalized iSP. Normalized iSP showed the least measurement variability. We propose that future investigations examining interhemispheric inhibition use normalized iSP for measurement consistency and the ability to compare results across studies. (C) 2017 Elsevier B.V. All rights reserved.