Assessing bioaccessibility and bioavailability of chlorinated organophosphorus flame retardants in sediments
Assessing bioaccessibility and bioavailability of chlorinated organophosphorus flame retardants in sediments
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评估沉积物中氯化有机磷阻燃剂的生物可及性和生物利用度
DOI：
10.1016/j.chemosphere.2017.09.017
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发表时间：
2017
期刊：
影响因子：
8.8
通讯作者：
Sun Cheng
中科院分区：
文献类型：
--
作者：
He Huan;Gao Zhanqi;Zhu Donglin;Guo Jiehong;Yang Shaogui;Li Shiyin;Zhang Limin;Sun Cheng
氯化有机磷阻燃剂（OPFRs）在沉积物中的分布规律已被广泛研究，但对其生物有效性的研究尚不多见。本研究探讨了固相微萃取（SPME）纤维和Tenax提取的适用性，以预测两个氯化OPFR：三（2-氯异丙基）磷酸盐和三（1，3-二氯-2-异丙基）磷酸盐，在沉积物中的生物有效性。我们的研究结果表明，SPME纤维和Tenax提取的浓度与测量的浓度在水生蠕虫（蚯蚓）显着相关。同时，测定了6 h和24 h的Tenax提取浓度，发现这两个时间段之间存在较强的线性关系，此外，6 h Tenax提取浓度与SPME纤维提取浓度也显著相关，且Tenax提取浓度远高于SPME纤维提取浓度。这些结果表明，SPME和Tenax提取方法的有效性，以预测沉积物中的氯化OPFRs的生物有效性，并发现Tenax提取比SPME提取更有前途。
The distribution of chlorinated organophosphate flame retardants (OPFRs) in sediments has been well documented, but the study about their bioavailability remains lacking. This study investigated the applicability of solid phase microextraction (SPME) fiber and Tenax extraction to predict the bioavailability of two chlorinated OPFRs: tri(2-chloroisopropyl) phosphate and tri(1,3-dichloro-2-isopropyl) phosphate, in sediments. Our results showed that both SPME fiber and Tenax extracted concentrations correlated significantly with the measured concentrations in the aquatic worm (Lumbriculus variegatus). We also measured the Tenax extracted concentrations at 6 and 24 h, and a strong linear relationship between these two time durations was found. In addition, the 6-h Tenax extracted concentrations also significantly correlated with the SPME fiber extracted concentrations, and the Tenax extracted concentrations were much higher than the SPME fiber extracted concentrations. These results demonstrate the efficiency of SPME and Tenax extraction methods to predict the bioavailability of chlorinated OPFRs in sediments, and it was found that the Tenax extraction is more promising than the SPME extraction.