Phenolic compounds: antioxidant and larvicidal potential ofSmilax brasiliensisSprengel leaves
Phenolic compounds: antioxidant and larvicidal potential ofSmilax brasiliensisSprengel leaves
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DOI：
10.1080/14786419.2018.1543678
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发表时间：
2020-09-01
影响因子：
2.2
通讯作者：
Rodrigues dos Santos Lima, Luciana Alves
中科院分区：
文献类型：
--
作者：
Amado, Paula Avelar;Fonseca Castro, Ana Hortencia;Rodrigues dos Santos Lima, Luciana Alves
Smilax brasiliensis是巴西塞拉多的一种药用植物。该植物的提取物和馏分进行了LC-DAD-MS分析。鉴定的成分包括糖基化和非糖基化的黄酮类化合物，特别是槲皮素，和苯丙素类化合物，如绿原酸。甲醇提取物和馏分的抗氧化活性明显高于商业抗氧化剂2，6-二叔丁基-4-甲基苯酚（BHT）。在二氯甲烷馏分中记录到85.83%的最大杀幼虫活性（LC 50 = 469.78 μ g mL（-1））。甲醇提取物及各组分对卤虫幼虫的毒性较低，表明C.致倦肌这些结果有助于S.巴西的。这些化合物首次在该物种中被鉴定，并鼓励对S的提取物和馏分中存在的化合物进行分离的额外工作。巴西的研究人员评估了将它们用作抗氧化剂天然来源的可能性，因为没有证明它们具有细胞毒性作用。
Smilax brasiliensisis a medicinal species of the Brazilian Cerrado. The extract and fractions of this plant were analysed by LC-DAD-MS. Identified constituents included glycosylated and non-glycosylated flavonoids, especially quercetin, and phenylpropanoids, such as chlorogenic acids. The antioxidant activity was significantly more pronounced for the methanol extract and fractions than that of the commercial antioxidant 2,6-di-tert-butyl-4-methylphenol (BHT). Maximum larvicidal activity of 85.83% was recorded in the dichloromethane fraction (LC50= 469.78 mu g mL(-1)). The methanol extract and fractions presented low toxicity to larvae of the shrimp brineArtemia salina,indicating selectivity forC. quinquefasciatus. These results contribute to the phytochemical study ofS. brasiliensis. These compounds were identified for the first time in this species and encourage additional work on the isolation of compounds present in the extract and fractions ofS. brasiliensisto evaluate the possibility of using them as natural sources of antioxidants, since cytotoxic effects were not demonstrated.