Survival differences among older dialysis patients in the southeast.
Survival differences among older dialysis patients in the southeast.
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东南部老年透析患者的生存差异。
DOI：
10.1016/s0272-6386(12)70302-5
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Flagg,E
中科院分区：
文献类型：
--
作者：
Brogan,D;Kutner,NG;Flagg,E
在美国，接受慢性透析治疗的老年终末期肾病(ESRD)患者的死亡率高于许多其他国家。虽然年龄增加、白人、男性和/或糖尿病被认为是生存的危险因素，但很少有关于老年透析患者的研究同时考虑多个预测变量及其相互作用。利用1982年至1986年佐治亚州和南卡罗来纳州的ESRD Network 20数据库中包含的信息，我们研究了1354名黑人和965名白人的住院情况和存活率，这些人在开始透析治疗时年龄在60岁或以上。生存时间用COX寿命表回归方法建模。老年黑人开始透析时的中位年龄为67.4%，而老年白人为68.7%(P=0.001)。黑人比白人(P<；0.001)更有可能患有与高血压或糖尿病相关的终末期肾病。在对高危患者天数进行调整后，白人患者的住院率增加了约25%。糖尿病相关性终末期肾病患者和非糖尿病相关性终末期肾病患者需要单独的多变量生存模型。在糖尿病患者中，白人和开始透析时年龄较大的患者的死亡率更高。在非糖尿病相关的终末期肾病患者中，开始透析时年龄较大的患者死亡率较高，但白人男性的年龄影响要强得多。我们的住院和死亡率数据支持这样的观点，即与黑人透析患者相比，白人患者的严重程度(或脆弱程度)未被测量。在非糖尿病相关的终末期肾病患者中，白人男性的年龄对生存的影响比黑人或白人女性更严重。我们在佐治亚州和南卡罗来纳州老年透析患者中观察到的高死亡率值得进一步研究；这些数据可能在一定程度上反映了与年龄、种族和性别匹配的对照组相比，患者的社会经济地位较低。
Older end-stage renal disease (ESRD) patients treated by chronic dialysis have higher mortality in the United States than in many other countries. While increasing age, white race, male sex, and/or diabetes are considered risk factors for survival, few studies of older dialysis patients have simultaneously considered multiple predictor variables and their interactions. Using information contained in the 1982 to 1986 ESRD Network 20 database for Georgia and South Carolina, we studied hospitalizations and survival of 1,354 blacks and 965 whites who were age 60 years or older when they began dialysis therapy. Survival time was modeled using the Cox life-table regression method. Older blacks’ median age at dialysis initiation was 67.4, compared with 68.7 for older whites (P = 0.001). Blacks were more likely than whites (P < 0.001) to have hypertension-related or diabetes-related ESRD. White patients experienced approximately 25% more hospitalization when adjustment was made for patient-days at risk. Separate multivariate survival models were required for patients with diabetes-related versus non-diabetes-related ESRD. Among diabetics, mortality was higher among whites and among patients who were older when they began dialysis. Among patients with nondiabetes-related ESRD, mortality was higher among patients who were older when they began dialysis, but the age effect was much stronger for white males. Our hospitalization and mortality data support the view that unmeasured severity (or frailty) differences characterize white as compared with black dialysis patients. Among non-diabetesrelated ESRD patients, the age effect on survival was more severe in white males than in blacks or in white females. The high mortality we observed among older dialysis patients in Georgia and South Carolina warrants further study; the data may in part reflect patients’ lower socioeconomic status compared with age, race, and sex-matched controls.
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DOI：
10.1093/ndt/6.1.5
发表时间：
1991
期刊：
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
影响因子：
--
作者：
H. Burger;G. Kootstra;F. D. de Charro;P. Leffers
通讯作者：
P. Leffers
60岁以上患者的维持性血液透析治疗。
DOI：
--
发表时间：
1985
期刊：
Proceedings of the European Dialysis and Transplant Association
影响因子：
--
作者：
C. Jacobs;A. Diallo;E. Balas;M. Nectoux;S. Etienne
通讯作者：
S. Etienne
DOI：
10.1016/s0272-6386(12)80765-7
发表时间：
1990
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
F. Port
通讯作者：
F. Port
高龄透析患者的死亡率、发病率和生活满意度。
DOI：
--
发表时间：
1984
期刊：
Transactions - American Society for Artificial Internal Organs
影响因子：
--
作者：
L. Westlie;A. Umen;S. Nestrud;C. Kjellstrand
通讯作者：
C. Kjellstrand
2,728 名终末期肾病患者的生存率。
影响因子：
8.9
作者：
W. Hellerstedt;W. J. Johnson;N. Ascher;C. Kjellstrand;Russell Knutson;F. Shapiro;S. Sterioff
通讯作者：
S. Sterioff