Nonimmersive Virtual Reality Mirror Visual Feedback Therapy and Its Application for the Treatment of Complex Regional Pain Syndrome: An Open-Label Pilot Study
Nonimmersive Virtual Reality Mirror Visual Feedback Therapy and Its Application for the Treatment of Complex Regional Pain Syndrome: An Open-Label Pilot Study
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DOI：
10.1111/j.1526-4637.2010.00819.x
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发表时间：
2010-01-01
期刊：
影响因子：
3.1
通讯作者：
Morita, Kiyoshi
中科院分区：
文献类型：
--
作者：
Sato, Kenji;Fukumori, Satoshi;Morita, Kiyoshi
目的：慢性疼痛，如幻肢痛和复杂区域疼痛综合征是很难治疗的，传统的药物治疗和侵入性神经阻滞并不总是有效的。中枢神经系统的可塑性发生在这些条件下，可能与疼痛有关。镜像视觉反馈疗法旨在恢复正常的皮质组织，并应用于慢性疼痛状况的治疗。然而，并非所有患者都能从这种治疗中获益。虚拟现实技术越来越多地吸引人们对医疗应用的关注，包括作为镇痛方式。一个先进的镜像视觉反馈系统与虚拟现实技术可能会增加止痛效果，并受益于更广泛的患者群体。在这项初步工作中，我们开发了一个虚拟现实镜像视觉反馈系统，并将其应用于复杂的区域疼痛综合征的治疗。设计。一个小型的开放标签病例系列。五名患有复杂区域疼痛综合征的患者在门诊接受了每周一次的虚拟现实镜像视觉反馈治疗，共五到八次。监测患者的持续用药和疼痛强度。结果：5名患者中有4名疼痛强度降低> 50%。其中两名患者结束了他们的访问我们的疼痛clinic after five semination.Conclusion.我们的研究结果表明，虚拟现实镜像视觉反馈治疗是一个很有前途的替代治疗复杂的区域疼痛综合征。进一步的研究是必要的，然后才得出结论，从虚拟现实镜像视觉反馈治疗提供的镇痛是扭转疼痛感知的适应不良变化的结果。
Objective.Chronic pain conditions such as phantom limb pain and complex regional pain syndrome are difficult to treat, and traditional pharmacological treatment and invasive neural block are not always effective. Plasticity in the central nervous system occurs in these conditions and may be associated with pain. Mirror visual feedback therapy aims to restore normal cortical organization and is applied in the treatment of chronic pain conditions. However, not all patients benefit from this treatment. Virtual reality technology is increasingly attracting attention for medical application, including as an analgesic modality. An advanced mirror visual feedback system with virtual reality technology may have increased analgesic efficacy and benefit a wider patient population. In this preliminary work, we developed a virtual reality mirror visual feedback system and applied it to the treatment of complex regional pain syndrome.Design.A small open-label case series. Five patients with complex regional pain syndrome received virtual reality mirror visual feedback therapy once a week for five to eight sessions on an outpatient basis. Patients were monitored for continued medication use and pain intensity.Results.Four of the five patients showed > 50% reduction in pain intensity. Two of these patients ended their visits to our pain clinic after five sessions.Conclusion.Our results indicate that virtual reality mirror visual feedback therapy is a promising alternative treatment for complex regional pain syndrome. Further studies are necessary before concluding that analgesia provided from virtual reality mirror visual feedback therapy is the result of reversing maladaptive changes in pain perception.