The birth of new neurons in the maternal brain: Hormonal regulation and functional implications.

The birth of new neurons in the maternal brain: Hormonal regulation and functional implications.
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DOI:
10.1016/j.yfrne.2016.02.004
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发表时间:
2016-04
影响因子:
7.4
通讯作者:
Sabihi S
Sabihi S
中科院分区:
医学1区
文献类型:
--
作者:
Leuner B;Sabihi S

文献摘要

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母亲的大脑具有显著的可塑性,并表现出多方面的神经修饰。神经发生已经成为母体大脑表现出可塑性的机制之一。这篇综述强调了目前已知的成年神经发生和相关激素机制的变化。我们还考虑了围产期大脑神经发生的功能后果,以及这一过程在产妇护理、认知功能和产后情绪中可能发挥的作用。最后,虽然大多数工作调查的影响,养育成人神经发生的母亲集中,一些研究检查了父亲,这些结果也进行了讨论。
The maternal brain is remarkably plastic and exhibits multifaceted neural modifications. Neurogenesis has emerged as one of the mechanisms by which the maternal brain exhibits plasticity. This review highlights what is currently known about peripartum-associated changes in adult neurogenesis and the underlying hormonal mechanisms. We also consider the functional consequences of neurogenesis in the peripartum brain and extent to which this process may play a role in maternal care, cognitive function and postpartum mood. Finally, while most work investigating the effects of parenting on adult neurogenesis has focused on mothers, a few studies have examined fathers and these results are also discussed.