Is transcription in sperm stationary or dynamic?
Is transcription in sperm stationary or dynamic?
复制标题
精子中的转录是静态的还是动态的?
DOI:
10.1262/jrd.2016-093
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发表时间:
2017-10-18
期刊:
影响因子:
--
通讯作者:
Wang D
中科院分区:
文献类型:
--
作者:
Ren X;Chen X;Wang Z;Wang D
Transcriptional activity is repressed due to the packaging of sperm chromatins during spermiogenesis. The detection of numerous transcripts in sperm, however, raises the question whether transcriptional events exist in sperm, which has been the central focus of the recent studies. To summarize the transcriptional activity during spermiogenesis and in sperm, we reviewed the documents on transcript differences during spermiogenesis, in sperm with differential motility, before and after capacitation and cryopreservation. This will lay a theoretical foundation for studying the mechanism(s) of gene expression in sperm, and would be invaluable in making better use of animal sires and developing reproductive control technologies.
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