Prevalence of depressive symptoms in Japanese male patients with chronic obstructive pulmonary disease
Prevalence of depressive symptoms in Japanese male patients with chronic obstructive pulmonary disease
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DOI：
10.1111/j.1440-1819.2010.02171.x
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发表时间：
2011-01-01
影响因子：
11.9
通讯作者：
Ozawa, Hiroki
中科院分区：
文献类型：
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作者：
Hayashi, Yoshika;Senjyu, Hideaki;Ozawa, Hiroki
目的：本研究的目的是利用医院焦虑和抑郁量表-抑郁亚量表（HADS-D）和流行病学研究中心抑郁量表（CES-D）这两种常用工具筛选稳定期慢性阻塞性肺疾病（COPD）患者的抑郁症状。此外，我们试图确定在通过CES-D和HADS-D评估的抑郁症状的患病率以及抑郁症状的预测因素方面是否存在差异。方法：采用CES-D和HADS-D对80例稳定期COPD门诊患者和51例稳定期COPD住院患者的抑郁症状进行评估。获得有关性别、受教育程度、体重指数、吸烟指数和肺功能的数据，以评估它们作为抑郁症状预测因子的独立贡献。结果：基于CES-D的抑郁症状患病率为29.8%，基于HADS-D的抑郁症状患病率为40.5%。MacNemar COPD严重程度测试和基于CES-D和HADS-D的抑郁症状结果分析显示了显著差异。Logistic回归分析表明，“严重程度”是CES-D评估的抑郁症状的预测因子，而“体重指数”、“教育水平”和“环境”是HADS-D评估的抑郁症状的预测因子。结论：用CES-D和HADS-D评估时，抑郁症状的患病率有所不同。造成这一差异的原因包括HADS-D在轻度COPD患者中经常检测到抑郁症状，以及HADS-D倾向受教育水平的强烈影响。相比之下，慢性阻塞性肺病的严重程度反映在CES-D中。根据应用的筛查工具，抑郁症状的患病率可能有所不同。
Aim:The objective of this study was to utilize commonly applied tools, the Hospital Anxiety and Depression Scale - Depression subscale (HADS-D) and the Center for Epidemiological Studies Depression Scale (CES-D), to screen for depressive symptoms in patients with stable chronic obstructive pulmonary disease (COPD). Furthermore, we sought to identify whether differences existed in the prevalence of depressive symptoms as assessed by CES-D and HADS-D, and predictors of depressive symptoms.Methods:The presence of depressive symptoms in 80 outpatients and 51 inpatients with stable COPD was assessed using the CES-D and HADS-D. Data regarding sex, educational level, body mass index, smoking index and pulmonary function were obtained to evaluate their independent contribution as predictors of depressive symptoms.Results:The prevalence of depressive symptoms was 29.8% based on CES-D and 40.5% based on HADS-D. A MacNemar test of COPD severity and analysis of the results of depressive symptoms based on CES-D and HADS-D revealed significant differences. Logistic regression analysis suggested that 'severity' is a predictor of depressive symptoms as assessed by CES-D, whereas 'body mass index', 'education level' and 'setting' were predictors of depressive symptoms as assessed by HADS-D.Conclusions:The prevalence of depressive symptoms differed when assessed with CES-D and HADS-D. The reasons behind this difference include the fact that HADS-D frequently detected depressive symptoms in patients with mild COPD as well as a tendency for HADS-D to be strongly influenced by education levels. In contrast, the severity of COPD was reflected in CES-D. It is possible that prevalence of depressive symptoms differs in accordance with the applied screening tool.