Identification of the Salmonella phage epsilon 34 tailspike gene.
Identification of the Salmonella phage epsilon 34 tailspike gene.
复制标题
沙门氏菌噬菌体 epsilon 34 tailspike 基因的鉴定。
DOI：
10.1016/j.gene.2006.09.013
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发表时间：
2007
期刊：
影响因子：
3.5
通讯作者：
Villafane,Robert
中科院分区：
文献类型：
--
作者：
Zayas,Milka;Villafane,Robert
为了从分子细节上了解脂多糖（LPS）与蛋白质之间的相互作用，采用分子遗传学方法，以噬菌体为模型系统。噬菌体ε34是一种沙门氏菌噬菌体，其尾刺蛋白（TSP）使用宿主LPS作为其初始宿主细胞受体。以往的研究表明，已被充分研究的沙门氏菌噬菌体P22尾部蛋白与ε34具有相似性。本研究报道了ε34TSP基因的鉴定及其初步鉴定。此外，还推导了ε34TSP结构的一些方面。
To understand the interaction between lipopolysaccharide (LPS) and proteins in molecular detail, a molecular genetic approach has been employed, using phage as a model system. The phage ε34is a Salmonella phage whose tailspike protein (TSP) uses the host LPS as its initial host cell receptor. Previous studies indicated that there was a similarity between the well-studied tail protein of Salmonella phage P22 and the ε34. This study reports the identification of the gene for the ε34TSP as well as its initial characterization. In addition, some aspects of the structure of the ε34TSP have been deduced.