Impact of olfactory impairment on quality of life and disability
Impact of olfactory impairment on quality of life and disability
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DOI：
10.1001/archotol.127.5.497
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发表时间：
2001-05-01
影响因子：
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通讯作者：
Reiter, ER
中科院分区：
文献类型：
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作者：
Miwa, T;Furukawa, M;Reiter, ER
目的：确定嗅觉丧失是否影响患者的生活质量或残疾水平。设计：使用问卷调查数据和临床数据库review.Setting：两所大学医学中心的嗅觉和味觉clinics.Patients：共1407例患者进行了测试，从1984年到1998年的嗅觉和味觉障碍。调查邮寄给1093例有异常测试分数的患者; 420例（38.4%）返回完成的调查。患者根据自我评价的嗅觉能力被分组为“受损”（报告持续赤字的国家）或“改善”的国家主要结果测量：比较两组患者对日常生活活动能力和生活质量问题的回答频率。结果：嗅觉受损组受嗅觉丧失影响的日常生活活动的平均（+/- SD）次数为4.70 +/- 3.56，改善组为0.61 +/- 1.58（P <0.001）。在具体的活动中，最常见的障碍是发现变质食物的能力（受损组与改善组，75%对12%; P < .001），气体泄漏（61%对8%; P < .001），或吸烟（50%对1%; P < .001）;进食（53%对12%，P < .001）;和烹饪（49%对12%; P < .001）。生活质量问题的差异主要体现在安全和饮食方面。改善组的总体生活满意度为87%，而受损组仅为50%（P <0.001）。结论：与嗅觉受损的患者相比，在先前记录的嗅觉丧失后报告持续性嗅觉受损的患者的残疾程度更高，生活质量更低。
Objective: To determine whether olfactory loss affects patients' quality of life or level of disability.Design: Retrospective survey using questionnaire data and clinic database review.Setting: Two university medical center smell and taste clinics.Patients: A total of 1407 patients were tested for smell and taste disturbances from 1984 through 1998. Surveys were mailed to 1093 patients who had abnormal test scores; 420 (38.4%) returned completed surveys. Patients were grouped by self-rated ability to smell as "impaired" (those reporting persisting deficits) or "improved" (those reporting no smell problem when surveyed).Main Outcome Measures: Response frequencies were compared between the 2 groups for questions regarding ability to perform common activities of daily living and quality-of-life issues.Results: Mean (+/- SD) number of activities of daily living affected by olfactory loss was 4.70 +/- 3.56 for the impaired group and 0.61 +/- 1.58 for the improved group (P < .001). Among specific activities, the most common cited impairments were ability to detect spoiled food (impaired vs improved groups, 75% vs 12%; P < .001), gas leaks (61% vs 8%; P < .001), or smoke (50% vs 1%; P < .001); eating (53% vs 12%, P < .001); and cooking (49% vs 12%; P < .001). Differences in quality-of-life issues were reported primarily in the areas of safety and eating. Overall satisfaction with life was reported by 87% of the improved group but only 50% of the impaired group (P < .001).Conclusions: Patients reporting persistent olfactory impairment after previously documented olfactory loss indicate a higher level of disability and lower quality of life than those with perceived resolution of olfactory compromise.