Rallying the exocyst as an autophagy scaffold.
Rallying the exocyst as an autophagy scaffold.
复制标题
将外囊聚集成自噬支架。
DOI：
10.1016/j.cell.2011.01.005
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发表时间：
2011
期刊：
影响因子：
64.5
通讯作者：
Subramani,Suresh
中科院分区：
文献类型：
--
作者：
Farre,Jean-Claude;Subramani,Suresh
蛋白质支架协调许多多组分信号复合物的组装。Bodemann等人（2011）现在表明，外囊（一种参与将运输囊泡束缚到质膜的蛋白质复合物）通过需要GTdR RalB的过程为自噬机制的组分提供组装和活化平台。
Protein scaffolds coordinate the assembly of many multicomponent signaling complexes. Bodemann et al. (2011) now show that the exocyst, a protein complex involved in tethering transport vesicles to the plasma membrane, provides an assembly and activation platform for components of the autophagy machinery via a process requiring the GTPase RalB.