Nitrogen dioxide and mortality: review and meta-analysis of long-term studies
Nitrogen dioxide and mortality: review and meta-analysis of long-term studies
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DOI：
10.1183/09031936.00114713
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发表时间：
2014-09-01
影响因子：
24.3
通讯作者：
Forastiere, Francesco
中科院分区：
文献类型：
--
作者：
Faustini, Annunziata;Rapp, Regula;Forastiere, Francesco
在几项流行病学研究中，暴露于环境中的二氧化氮（NO2）与死亡率增加有关，但问题仍然是，二氧化氮是否对健康影响负有直接责任，还是仅仅是其他污染物（包括颗粒物）的一个指标。本综述的目的是提供二氧化氮对死亡率的长期影响的综合估计，这可能对健康影响评估有用。我们选择了2004年至2013年发表的23篇论文，评估了二氧化氮与死亡率之间的关系，并评估了颗粒物暴露的影响。对19项研究进行随机效应荟萃分析。NO2年浓度每增加10 μ g·m(-3)，对死亡率的综合影响为1.04 (95% CI 1.02 ~ 1.06)；颗粒物对死亡率的综合影响为1.05 （95% CI 1.01 ~ 1.09）
Exposure to ambient nitrogen dioxide (NO2) has been linked to increased mortality in several epidemiological studies but the question remains of whether NO2 is directly responsible for the health effects or is only an indicator of other pollutants, including particulate matter. The aim of the present review was to provide pooled estimates of the long-term effects of NO2 on mortality, which are potentially useful for health impact assessment.We selected 23 papers, published from 2004 to 2013, evaluating the relationship between NO2 and mortality, also including an assessment of the effect of particulate matter exposure. A random-effects meta-analysis was carried out on 19 studies.The pooled effect on mortality was 1.04 (95% CI 1.02-1.06) with an increase of 10 mu g.m(-3) in the annual NO2 concentration and 1.05 (95% CI 1.01-1.09) for particulate matter