Studies on the equilibria and kinetics of the reactions of peroxidases with ligands. I. The reaction of ferroperoxidases with carbon monoxide.
Studies on the equilibria and kinetics of the reactions of peroxidases with ligands. I. The reaction of ferroperoxidases with carbon monoxide.
复制标题
过氧化物酶与配体反应的平衡和动力学研究。
DOI：
10.1021/bi00888a016
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发表时间：
1965
期刊：
影响因子：
2.9
通讯作者：
R. Zito
中科院分区：
文献类型：
--
作者：
D. Kertesz;E. Antonini;M. Brunori;J. Wyman;R. Zito
dennis Kertesz, Eraldo Antonini, Maurizio Brunori， Jeffries Wyman和Romano Zito摘要：研究了辣根和无花果铁过氧化物酶与一氧化碳反应的平衡和动力学。对于两种过氧化物酶，在20时，平衡常数(L)约为4.5 X 106 m_1，结合速度常数（/'）约为4 X 103 M-1sec-1。L过氧化酶是一组异质血红素蛋白，在过氧化物和电子供体之间的反应中起催化剂的作用（Paul, 1963; Nichols, 1962; Saunders et al., 1964）。过氧化物酶的铁质形式被认为与过氧化物结合形成一系列配合物，这些配合物又与可氧化的底物反应（Keilin和Mann, 1937; theorem, 1941; Chance, 1951）。
Denis Kertesz, Eraldo Antonini, Maurizio Brunori, Jeffries Wyman, and Romano Zito abstract: The equilibrium and kinetics of the reaction of horseradish and fig ferroperoxidases with carbon monoxide have been studied. For both peroxidases, at 20, the equilibrium constant (L) is about 4.5 X 106 m_1 and the combination velocity constant (/') about 4 X 103 M-1sec-1.. L eroxidases are a heterogeneous group of heme pro-teins which may act as catalysts in reactions between peroxides and an electron donor (Paul, 1963; Nichols, 1962; Saunders et al., 1964). The ferri form of peroxi-dase is thought to combine with peroxidesto give a series of complexes whichin turn react with the oxi-dizable substrates (Keilin and Mann, 1937; Theorell, 1941; Chance, 1951).