Histone Modifications: Epigenetic Mediators of Environmental Exposure Memory.
Histone Modifications: Epigenetic Mediators of Environmental Exposure Memory.
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DOI：
10.1177/2516865718803641
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发表时间：
2018
影响因子：
2.2
通讯作者：
Allard P
中科院分区：
文献类型：
--
作者：
Camacho J;Allard P
生物体如何保留祖先环境暴露的记忆是一个仍然知之甚少的现象。我们小组和其他人最近发表的关于环境诱导的跨代效应的工作已经确定了一系列机制，特别关注组蛋白修饰，这些机制揭示了驱动长期世代效应的潜在表观遗传过程。
How organisms retain a memory of ancestral environmental exposure is a phenomenon that is still poorly understood. Recently published work by our group and others, regarding environmentally induced transgenerational effects, have identified an array of mechanisms, with a particular focus on histone modifications, that shed some light on the underlying epigenetic processes driving long-term generational effects.