Emergence in Asian countries of Staphylococcus aureus with reduced susceptibility to vancomycin
Emergence in Asian countries of Staphylococcus aureus with reduced susceptibility to vancomycin
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DOI：
10.1128/aac.48.12.4926-4928.2004
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发表时间：
2004-12-01
影响因子：
4.9
通讯作者：
Lee, NY
中科院分区：
文献类型：
--
作者：
Song, JH;Hiramatsu, K;Lee, NY
为了解亚洲地区耐甲氧西林金黄色葡萄球菌(MRSA)中对万古霉素敏感性降低的金黄色葡萄球菌(MRSA)的流行情况，用脑心输注琼脂平板筛选来自亚洲12个国家的1357株临床分离的MRSA，每升含4 mg万古霉素。群体分析证实存在对万古霉素异质中介耐药(HVISA)的菌株。在琼脂平板上培养的347株(25.6%)MRSA中，58株(4.3%)为hVISA。在印度、韩国、日本、菲律宾、新加坡、泰国和越南都发现了hVISA毒株。然而，在本次调查的亚洲国家分离的MRSA中，既没有发现万古霉素中间的金黄色葡萄球菌，也没有发现万古霉素耐药的金黄色葡萄球菌。
To investigate the prevalence of Staphylococcus aureus with reduced susceptibility to vancomycin among methicillin-resistant S. aureus (MRSA) strains in Asian countries, a total of 1,357 clinical isolates of MRSA collected from 12 Asian countries were screened by using brain heart infusion agar plates containing 4 mg of vancomycin per liter. The presence of strains that were heterointermediately resistant to vancomycin (hVISA) was confirmed by population analysis. Of 347 (25.6%) MRSA isolates that grew on the screening agar plates, 58 isolates (4.3%) were hVISA. hVISA strains were found in India, South Korea, Japan, the Philippines, Singapore, Thailand, and Vietnam. However, neither vancomycin-intermediate S. aureus nor vancomycin-resistant S. aureus isolates were found among MRSA isolates from Asian countries in this survey.