Response properties of temporomandibular joint mechanosensitive neurons in the trigeminal sensory complex of the rabbit.
Response properties of temporomandibular joint mechanosensitive neurons in the trigeminal sensory complex of the rabbit.
复制标题
兔三叉神经感觉复合体颞下颌关节机械敏感神经元的响应特性。
DOI：
10.1007/s00221-012-3200-y
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发表时间：
2012
期刊：
影响因子：
2
通讯作者：
Watanabe M.
中科院分区：
文献类型：
--
作者：
Suzuki O;Tsuboi A;Tabata T;Takafuji Y;Sakurai T;Watanabe M.
在46只家兔上观察了髁突被动运动时三叉神经感觉复合体（Vcomp）内颞下颌关节运动敏感神经元（TMJ神经元）的神经生理特性。用微电极记录颞下颌关节Vcomp吻侧部神经元的放电，同时用计算机控制的机械刺激器和手动移动离体髁突。从脑干共记录到443个神经元对面部和口腔的机械刺激作出反应。21个颞下颌关节神经元从三叉神经感觉主核（NVsnpr）的背侧部分，三叉神经脊核的口侧亚核，三叉神经运动核周围的网状结构进行了检测。TMJ神经元主要位于NVsnpr的背嘴侧部。记录的TMJ单位中，90%为缓慢适应，26%伴有静息放电.大部分（86%）的颞下颌关节单位对髁突的前向和/或腹向运动有反应，半数对髁突的单向运动敏感。在离体髁突前移5 mm范围内，颞下颌关节单位放电频率随髁突前移和等速（5 mm/s）的增加而增加。基于这些结果，我们得出结论，感觉信息处理的颞下颌关节神经元编码至少关节的位置和位移在生理范围内的下颌位移。
The neurophysiological properties of neurons sensitive to TMJ movement (TMJ neurons) in the trigeminal sensory complex (Vcomp) during passive movement of the isolated condyle were examined in 46 rabbits. Discharges of TMJ neurons from the rostral part of the Vcomp were recorded with a microelectrode when the isolated condyle was moved manually and with a computer-regulated mechanostimulator. A total of 443 neurons responding to mechanical stimulation of the face and oral cavity were recorded from the brainstem. Twenty-one TMJ neurons were detected rostrocaudally from the dorsal part of the trigeminal principal sensory nucleus (NVsnpr), subnucleus oralis of the trigeminal spinal nucleus, and reticular formation surrounding the trigeminal motor nucleus. Most of the TMJ neurons were located in the dorso-rostral part of the NVsnpr. Of the TMJ units recorded, 90 % were slowly adapting and 26 % had an accompanying resting discharge. The majority (86 %) of the TMJ units responded to the movement of the isolated condyle in the anterior and/or ventral directions, and half were sensitive to the condyle movement in a single direction. The discharge frequencies of TMJ units increased as the condyle displacement and constant velocity (5 mm/s) increased within a 5-mm anterior displacement of the isolated condyle. Based on these results, we conclude that sensory information is processed by TMJ neurons encoding at least joint position and displacement in the physiological range of mandibular displacement.