The Virtual Physiological Human TOOLKIT

The Virtual Physiological Human TOOLKIT
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DOI:
10.1098/rsta.2010.0144
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发表时间:
2010-08-28
影响因子:
5
通讯作者:
Coveney, Peter V.
Coveney, Peter V.
中科院分区:
综合性期刊2区
文献类型:
--
作者:
Cooper, Jonathan;Cervenansky, Frederic;Coveney, Peter V.

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虚拟生理人(VPH)是一项主要的欧洲电子科学计划,旨在支持针对患者的计算机模型的开发及其在个性化和预测性医疗保健中的应用。VPH卓越网络(VPH- noe)项目的任务是促进各个VPH项目之间的互动,并解决共同关心的问题。一个关键的交付成果是“VPH工具包”——一个工具、方法和服务的集合,以支持和实现VPH研究,整合和扩展整个欧洲的现有工作,以实现更大的互操作性和可持续性。由于该领域的多样性,单一的单一“工具包”无法满足VPH的需求。相反,VPH工具包应该更多地被视为相关技术的“工具箱”,围绕一组通用标准进行交互。后者适用于工具所使用的信息,包括任何数据和VPH模型本身,也适用于所涉及的实体和概念的命名和分类。此外,现有的技术和方法需要广泛传播,相关的工具和服务需要容易被研究人员找到。因此,VPH- noe为VPH社区创建了一个在线资源,以满足这一需求。它包括一个数据库的工具,方法和服务的VPH研究,与Web前端。它具有搜索数据库、添加或更新条目以及提供关于条目的用户反馈的功能。任何人都欢迎贡献。
The Virtual Physiological Human (VPH) is a major European e-Science initiative intended to support the development of patient-specific computer models and their application in personalized and predictive healthcare. The VPH Network of Excellence (VPH-NoE) project is tasked with facilitating interaction between the various VPH projects and addressing issues of common concern. A key deliverable is the 'VPH TOOLKIT'-a collection of tools, methodologies and services to support and enable VPH research, integrating and extending existing work across Europe towards greater interoperability and sustainability.Owing to the diverse nature of the field, a single monolithic 'toolkit' is incapable of addressing the needs of the VPH. Rather, the VPH TOOLKIT should be considered more as a 'toolbox' of relevant technologies, interacting around a common set of standards. The latter apply to the information used by tools, including any data and the VPH models themselves, and also to the naming and categorizing of entities and concepts involved.Furthermore, the technologies and methodologies available need to be widely disseminated, and relevant tools and services easily found by researchers. The VPH-NoE has thus created an online resource for the VPH community to meet this need. It consists of a database of tools, methods and services for VPH research, with a Web front-end. This has facilities for searching the database, for adding or updating entries, and for providing user feedback on entries. Anyone is welcome to contribute.