A case of familial adenomatous polyposis with protein-losing enteropathy treated by laparoscopic total colorectal resection: A literature review.
A case of familial adenomatous polyposis with protein-losing enteropathy treated by laparoscopic total colorectal resection: A literature review.
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腹腔镜全结直肠切除术治疗家族性腺瘤性息肉病伴蛋白丢失性肠病一例文献综述
DOI：
10.1111/ases.13099
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Baba H.
中科院分区：
文献类型：
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作者：
Tubakihara H;Sawayama H;Komohara Y;Miyamoto Y;Ogawa K;Ohuchi M;Yoshida N;Baba H.
家族性腺瘤性息肉病（FAP）伴蛋白质丢失性肠病是一种罕见的疾病，很难在医学上治疗。1例74岁女性患者因主诉厌食被转诊至我院。下消化道内视镜检查显示从升结肠到直肠的多发性腺瘤，以及乙状结肠和降结肠的腺癌。实验室检查结果显示低白蛋白血症（白蛋白1.6 mg/dl）。使用99 mTc-HSAD进行的蛋白质渗漏造影发现蛋白质从结肠渗漏。尽管给予高热输注，但营养状况未改善，需要输注白蛋白。患者接受了腹腔镜全直肠结肠切除术、回肠袋-肛门吻合术和临时回肠造口术。术后病程良好，低白蛋白血症在几周内恢复正常。患者接受了暂时性回肠造口逆转术。在这里，我们报告了一例FAP伴蛋白丢失性肠病的病例，该病例接受了腹腔镜全直肠结肠切除术，从而改善了蛋白泄漏和癌症治疗。
Familial adenomatous polyposis (FAP) with protein‐losing enteropathy is a rare disorder and is difficult to treat medically. A 74‐year‐old female patient was referred to our hospital with a chief complaint of anorexia. Lower gastrointestinal endoscopy showed multiple adenomas from the ascending colon to the rectum and adenocarcinoma in the sigmoid colon and descending colon. Laboratory findings showed hypoalbuminemia (albumin 1.6 mg/dl). Protein leak scintigraphy using 99mTc‐HSAD found a protein leak from the colon. Although hypercaloric infusion was administered, the nutritional status was not improved and albumin transfusion was required. The patient underwent laparoscopic total proctocolectomy, ileal pouch‐anal anastomosis, and temporary ileostomy. She had a good postoperative course and the hypoalbuminemia normalized in a few weeks. The patient underwent temporary ileostomy reversal. Here we report a case of FAP with protein‐losing enteropathy who underwent laparoscopic total proctocolectomy, which resulted in improvement of the protein leak as well as cancer treatment.