Second malignant neoplasms following radiotherapy.
Second malignant neoplasms following radiotherapy.
复制标题
放疗后第二次恶性肿瘤。
DOI:
10.3390/ijerph9124744
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发表时间:
2012-12-18
影响因子:
--
通讯作者:
Kumar S
中科院分区:
文献类型:
--
作者:
Kumar S
More than half of all cancer patients receive radiotherapy as a part of their treatment. With the increasing number of long-term cancer survivors, there is a growing concern about the risk of radiation induced second malignant neoplasm [SMN]. This risk appears to be highest for survivors of childhood cancers. The exact mechanism and dose-response relationship for radiation induced malignancy is not well understood, however, there have been growing efforts to develop strategies for the prevention and mitigation of radiation induced cancers. This review article focuses on the incidence, etiology, and risk factors for SMN in various organs after radiotherapy.
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