ACTION SPECTRUM FOR PHOTOTHERAPY OF PSORIASIS
ACTION SPECTRUM FOR PHOTOTHERAPY OF PSORIASIS
复制标题
DOI：
10.1111/1523-1747.ep12520022
复制
发表时间：
1981-01-01
影响因子：
6.5
通讯作者：
JAENICKE, KF
中科院分区：
文献类型：
--
作者：
PARRISH, JA;JAENICKE, KF
使用单色仪，测定了254-313 nm之间辐射的银屑病UV光疗的作用光谱，并与未累及邻近皮肤的红斑的作用光谱进行了比较。观察了不同剂量的254、280、290、296、300、304和313 nm辐射的每日照射。254、280和290 nm的波长是致红斑的，但即使在最小红斑剂量的10-50倍下也没有治疗作用。在其他波长下，两种作用光谱相似。固定日剂量在较低的累积剂量下清除，而日剂量递增。所需的少量亚致辐射照射剂量表明，单色辐射可能比宽带辐射源更有优势。
Using a monochromator the action spectrum for UV phototherapy of psoriasis was determined for radiation between 254-313 nm and compared to the action spectrum for erythema of uninvolved adjacent skin. Daily exposures of different doses of 254, 280, 290, 296, 300, 304 and 313 nm radiation were observed. Wavelengths of 254, 280 and 290 nm were erythemogenic but not therapeutic even at 10-50 times the minimal erythema dose. At other wavelengths, the 2 action spectra were similar. Fixed daily doses cleared at lower cumulative dose than did incrementally increased daily doses. The small number of suberythemogenic exposure doses required suggested that monochromatic radiation may have advantages over broadband sources.