Benzimidazole derivatives as potential anticancer agents.

Benzimidazole derivatives as potential anticancer agents.
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DOI:
10.2174/138955713804999847
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发表时间:
2013-02
期刊:
Mini reviews in medicinal chemistry
影响因子:
--
通讯作者:
Ahmed A. El Rashedy;H. Aboul‐Enein
Ahmed A. El Rashedy;H. Aboul‐Enein
中科院分区:
其他
文献类型:
--
作者:
Ahmed A. El Rashedy;H. Aboul‐Enein

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Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.