Self-assembly of carbohydrate-based block copolymer systems: glyconanoparticles and highly nanostructured thin films
Self-assembly of carbohydrate-based block copolymer systems: glyconanoparticles and highly nanostructured thin films
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基于碳水化合物的嵌段共聚物系统的自组装：聚糖纳米颗粒和高度纳米结构的薄膜
DOI：
10.1038/s41428-021-00604-w
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发表时间：
2022
期刊：
影响因子：
2.8
通讯作者：
Borsali Redouane
中科院分区：
文献类型：
--
作者：
Li Hong;Mumtaz Muhammad;Isono Takuya;Satoh Toshifumi;Chen Wen-Chang;Borsali Redouane
碳水化合物是一种可持续的材料来源，由于其“绿色”方面、生物相容性、生物降解性和生物识别特性而吸引了越来越多的关注。它们在宏观尺度上的工业应用为生物基材料提供了新的解决方案，它们已应用于不同的领域，如化妆品，健康，包装或微电子。为了获得更多的理解并将这些系统纳入新的挑战/应用程序和设备（例如，生物纳米电子学）响应于向生物基经济的转变，在纳米尺度上控制它们的自组装是非常重要的。这一直是我们的工作在过去十年的目标，我们已经使用“点击化学”，并开发了一类新的线性碳水化合物为基础的（所谓的高χ）二嵌段共聚物系统，通过自组装，在高度纳米结构的亚10纳米分辨率的薄膜。在这篇集中的综述中，我们总结了一些最近的工作，说明了自组装特性，导致设计的糖纳米粒子和高度纳米结构的薄膜可能在不同的应用和生物标志物具有重要意义。
Carbohydrates constitute a sustainable source of materials that has attracted growing interest due to their “green” aspects, biocompatibility, biodegradability and biorecognition properties. Their industrial applications at the macroscopic scale offer new solutions for biobased materials, and they have been applied in different sectors, such as cosmetics, health, packaging, or microelectronics. To gain more understanding and incorporate these systems into new challenges/applications and devices (e.g., bionanoelectronics) in response to the transition to a biobased economy, it is of great importance to control their self-assembly at the nanoscale. This has been the aim of our work during the past decade—we have used “click chemistry” and developed a new class of linear carbohydrate-based (so-called high χ) diblock copolymer systems resulting, via self-assembly, in highly nanostructured sub-10-nm-resolution thin films. In this focused review, we summarize some recent work illustrating the self-assembly properties leading to the design of glyconanoparticles and highly nanostructured thin films potentially of great importance in different applications and biomarkers.